July 2007 in “Journal of Generic Medicines” The UK High Court revoked Lundbeck's patent for Escitalopram, and second medical use claims based on dosage were not considered novel.
30 citations
,
June 2008 in “Dermatologic Surgery” In this study, the SAFE System for follicular unit extraction demonstrated a favorable average follicle transection rate of 6.14% and is accessible for physicians with basic technical skills, showing promise for wider adoption.
27 citations
,
November 2008 in “Facial Plastic Surgery” This article outlines the technical aspects, benefits, and challenges of follicular unit extraction for hair transplantation, but it reports no new clinical findings.
27 citations
,
January 2006 in “Dermatologic Surgery” This study found that the SAFE System may improve follicular unit extraction by reducing follicle transection rates and broadening patient eligibility, with only minor adverse reactions reported.
20 citations
,
January 2006 in “Clinics in Plastic Surgery” This article discusses the benefits of tumescent surgery, such as reduced blood loss and pain control, but reports no new clinical findings.
7 citations
,
February 2012 in “Facial Plastic Surgery” This article discusses the mini-lift as a cosmetic procedure for minor cheek and neck laxity, emphasizing its benefits like quicker recovery and minimal incisions, but provides no new clinical data.
3 citations
,
May 2020 in “Annals of the Academy of Medicine Singapore” Hair dye can cause serious scalp issues, including skull erosion.
1 citations
,
November 2009 in “Cambridge University Press eBooks” This article reports that follicular unit extraction is a minimally invasive hair restoration technique that avoids linear scarring and reduces donor-site pain compared to traditional strip harvesting methods.
1 citations
,
January 2006 in “Dermatologic Surgery” The SAFE System may reduce hair transplant transection rates but has been critiqued for not being as minimally invasive as claimed.
April 2025 in “WORLD JOURNAL OF PLASTIC SURGERY” This study reported that stem cells derived from semi-solid bone marrow improved the healing of diabetic incision wounds in rats by increasing epidermal thickness and blood vessel growth, and reducing hair follicle destruction, cellular penetration, diffuse fibrosis, and necrosis compared to control groups.
55 citations
,
September 2014 in “Development” In this study, mouse sweat gland development relied on a regulatory sequence initiated by Wnt/β-catenin signaling, and disruptions in Wnt, Eda, or Shh pathways led to distinct developmental failures.
34 citations
,
August 2003 in “Clinical and Experimental Dermatology” This study found that hair diameter increases toward the scalp during pregnancy, a novel observation compared to the normal decrease seen in nonpregnant women.
25 citations
,
January 2009 in “Oral and Maxillofacial Surgery Clinics of North America” This article reviews complications associated with modern hair transplant surgery and discusses their treatment and prevention but reports no new clinical results.
14 citations
,
March 2017 in “Plastic and reconstructive surgery. Global open” In this study, various types of minor hair follicle damage were observed during follicular unit extraction, with paring and hair bulb injury being more apparent under microscopic examination.
13 citations
,
August 2016 in “Journal of Cosmetic Dermatology” This study found that intradermal injection of normal saline before follicular unit extraction significantly reduced wound size and skin mass removed compared to acute extraction, suggesting it minimizes skin injury in this procedure.
8 citations
,
January 2015 in “Journal of Cutaneous Medicine and Surgery” This review discusses the development of surgical hair restoration techniques and highlights the potential of hair follicle cell cloning to address current limitations.
5 citations
,
September 2003 in “Archives of Facial Plastic Surgery” This article discusses the follicular-unit grafting technique for hair transplantation and reports no clinical results; the authors highlight its potential for achieving natural-appearing outcomes but note the procedure's complexity.
2 citations
,
July 2014 in “Irish Journal of Medical Science” The meeting discussed medical findings, including benefits of certain treatments for cancer and heart conditions, and highlighted issues like poor adherence to preventive measures and skill gaps among interns.
This article reviews surgical techniques for addressing scalp defects and highlights hair restoration as a cosmetic improvement strategy, but it reports no new clinical results.
January 2026 in “Archive ouverte UNIGE (University of Geneva)” This narrative review examined skin-sparing techniques in gynecomastia surgery and found satisfactory thoracic remodeling with acceptable morbidity and reduced scarring, but acknowledged methodological differences that limit decisive conclusions.
This historical review discusses the ancient Egyptians' advanced wound-healing techniques, including the use of honey and moldy bread, and reports no new clinical results.
175 citations
,
April 1982 in “Journal of The American Academy of Dermatology” This study found that oral isotretinoin achieved good to excellent clinical results in treating severe inflammatory acne, severe rosacea, and gram-negative folliculitis.
122 citations
,
July 1990 in “Teratology” This study found that oral administration of finasteride to pregnant rats caused dosage-related developmental toxicities, including hypospadias and decreased anogenital distance in male offspring.
89 citations
,
March 2018 in “The Journal of Dermatology” This review presents various trichoscopic findings for diagnosing alopecia areata but reports no new clinical results, emphasizing that no single marker is pathognomonic and multiple features should be considered together.
62 citations
,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
44 citations
,
November 2011 in “The Journal of Dermatology” This review discusses recent advancements in the management and diagnosis of primary cicatricial alopecias but reports no new clinical results; emerging insights suggest sebaceous gland dysfunction may play a role in their etiopathogenesis.
37 citations
,
January 1991 in “Reproductive Toxicology” The study observed that finasteride reduced fertility in male Sprague-Dawley rats by impairing the formation of copulatory plugs, an effect considered specific to rats and not applicable to species without this reproductive feature.
28 citations
,
July 2011 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This case report describes a serious complication of follicular unit extraction, where donor-site necrosis led to cicatricial alopecia, but was successfully treated with two-stage surgery using tissue expanders.
23 citations
,
December 2020 in “Frontiers in Cell and Developmental Biology” This review explores recent insights into how intrinsic gene oscillations and molecular interactions in hair follicle stem cells contribute to their regenerative potential, with potential implications for regenerative medicine, but reports no new clinical results.
11 citations
,
June 2005 in “Journal of Cosmetic Dermatology” Lasers in hair transplantation show promise but are not yet standard, with current methods causing some side effects and needles still being preferred for creating recipient sites.