Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review proposes focusing on relationships between neuroactive steroids and psychiatric disorder symptoms, rather than relying on traditional disorder classifications, and reports no new clinical findings.

This study found that ectopic expression of Whn in transgenic mice caused impaired differentiation in epidermis and hair follicles, with hair growth defects and severe urinary tract issues leading to hydronephrosis.

This study found that brain-derived neurotrophic factor (BDNF) inhibited hair shaft elongation and induced premature catagen development in cultured human hair follicles, partially through transforming growth factor β2.

This review discusses the potential therapeutic effects of targeting the endocannabinoid system for chemotherapy-induced peripheral neuropathy and reports no new clinical results, highlighting the need for ongoing research.

This study reports the creation of rat liver stem cell lines that can differentiate into hepatocytes and suggests they might be useful for pharmacological and regenerative medicine applications.

In this study, hair follicle stem cells from ND-GFP transgenic mice were observed to be pluripotent, effectively repairing peripheral nerve and spinal cord injuries in mouse models.

This study reviews the mechanisms by which SARS-CoV-2 may impact male fertility, noting potential disruptions in spermatogenesis and hormone secretion, and underscores the need for follow-up in recovered men.

This review highlighted the pharmacological potential of Mor, noting its protective effects on the kidneys, liver, bones, nervous system, heart, digestive system, skin, and lungs, as well as its anti-obesity and anti-inflammatory properties, revealing areas for future research.

This study observed that direct exposure to androgens in Western clawed frogs differentially affects thyroid receptor and deiodinase gene expression in male and female tissues, offering insight into sex-specific metabolic pathway activation.

This study investigated protein expression changes during mouse hair follicle cycles and suggested their involvement in biological networks, potentially identifying targets for hair disease therapy.

This study found that epidermal melanocytes can regenerate hair follicles, whereas non-cutaneous or dermal melanocytes cannot, suggesting two distinct melanocyte lineages with potential implications for melanocyte-related diseases.

This review examines the impact of polycystic ovary syndrome on reproductive health, its pathophysiology, clinical manifestations, and emerging therapies, and reports no new findings; the authors emphasize the need for individualized treatment strategies.

This review discusses the role of platelet-rich plasma in assisted reproductive technology for enhancing endometrial receptivity and reports promising outcomes.

This study provides evidence that long-term deregulation of the circadian rhythm in humans affects the regenerative properties of skin and hair precursor cells by altering clock pathway protein expression.

This review discusses the role and therapeutic potential of mesenchymal cell-derived exosomes in organ development and disease treatment, highlighting their application in cell-free therapeutic strategies and current challenges faced in their use.

This study found that novel compounds moderately inhibited 5α-reductase type 1 activity compared to finasteride, offering valuable data on structure-activity relationships.

This study found that hair follicle stem cells are multipotent and can enhance nerve regeneration and function in mice, showing potential as an accessible source for treating peripheral nerve injuries.

In this study, peptide-based nanoparticles were successfully used to deliver the CRISPR-Cas9 system into cancer cells, effectively targeting and editing KRAS mutations, suggesting promising therapeutic potential for cancer treatment.

This biographical abstract highlights George Rogers' pioneering contributions to the understanding of keratin molecular structure and keratinisation biochemistry, including the application of electron microscopy to hair ultrastructure and the discovery of enzymes and gene transcription processes relevant to keratin proteins.

This study found that the HoxC gene cluster is crucial for the development of hair and nails in mice, with key regulation by two mammalian-specific enhancers.

This chapter reviews pharmacodynamic evaluations in endocrine disorders focusing on oral antidiabetics, insulin analogues, and hormone interactions, but reports no new results.

This study found that human hair follicles can be used to generate induced pluripotent stem cells, which can then efficiently differentiate back into keratinocytes.

This abstract contains no research findings; it outlines website features and access options for the JAMA network's publications.

This study found that inhaling toluene reduces core temperature in mice, with GABA receptors and neurosteroids involved at 4000 ppm, but different mechanisms contributing at 6000 ppm.

This study discovered that calcium dependent protein kinase 1 (CPK1) directly activates cyclic nucleotide-gated channels 5, 6, and 9, promoting root hair growth in Arabidopsis by regulating Ca²⁺ signaling.

A feedback loop between LRH and RSL4 controls root hair growth in Arabidopsis.

This study found significant variation in tissue mutant load in individuals with the T8993G mutation, which complicates genetic counseling and may inform genotype-phenotype correlations, especially using hair bulb mtDNA analysis.

This review examines the pathophysiology of PCOS and reports that myoinositol may improve menstrual regularity, insulin sensitivity, and reproductive outcomes, with comparable efficacy to metformin and often better tolerability.

This study used whole-genome resequencing to analyze genetic diversity and selection in 17 rabbit breeds, identifying genes linked to traits like coat color and body size, which could inform breeding and conservation efforts.

This study concluded that CNGC14 is a calcium-permeable channel crucial for polarized tip growth in Arabidopsis root hairs, but other channels may also influence the observed calcium influx.