April 2019 in “Journal of Drug Delivery and Therapeutics” In this study, researchers developed poly herbal shampoo formulations using natural herbs like Ashwagandha and Amla, which showed effective hair care benefits including strengthening hair growth and preventing dandruff while maintaining safe pH and foaming capacity; however, stability studies for these formulations are needed.
April 2017 in “Journal of Investigative Dermatology” This study found that pre-treatment with a stimulating cream shampoo significantly increased Minoxidil penetration into hair follicles and the scalp compared to using Minoxidil alone.
April 2016 in “Journal of Investigative Dermatology” This study found that a stimulating cream shampoo enhances the penetration of Minoxidil into hair follicles and scalp in a laboratory setting.
This abstract discusses telogen effluvium, a type of hair loss that can occur after pregnancy or extreme stress, and the authors mention a shampoo product that is claimed to help prevent or recover from this condition.
43 citations
,
October 2002 in “International Journal of Cosmetic Science” This study found that 1% ketoconazole and 1% piroctone olamine shampoos increased hair shaft thickness and reduced hair shedding in men with telogen effluvium and androgenic alopecia associated with dandruff.
20 citations
,
January 1990 in “Journal of dermatological treatment” This study found that both ketoconazole 2% shampoo and selenium sulphide are effective for dandruff treatment, but ketoconazole also reduces hair growth.
9 citations
,
June 2011 in “International Journal of Cosmetic Science” This study found that a commercially available shampoo significantly increased hair counts and reduced hair shedding in Korean subjects with alopecia over 16 weeks.
5 citations
,
August 2021 in “Journal of drug delivery and therapeutics” This study evaluated a herbal shampoo containing fermented rice water and traditional herbs, finding it safe and effective for reducing hair fall, with notable properties like good foam ability, cleansing action, and soothing qualities.
5 citations
,
January 1992 This study found that dimethicone with high molecular weight improved hair surface characteristics, while dimethicone copolyol and amodimethicone enhanced manageability by reducing friction or aiding styling on damaged hair.
4 citations
,
January 2023 in “Veterinary Sciences” This study found that applications of a shampoo and mousse containing plant extracts improved coat quality in dogs with a chronic keratinisation disorder without affecting skin hydration or hair lipids over the study period.
2 citations
,
October 2021 in “International journal of pharmaceutical chemistry and analysis” This research developed a herbal shampoo powder using traditional plant ingredients and found it met ideal physicochemical standards, but further studies are needed to enhance its quality, performance, and safety.
1 citations
,
November 2025 in “American Journal of Medical Science and Technology” In this study, researchers formulated a herbal shampoo using ingredients like Reetha, Shikakai, Aloe Vera, and Amla, and found it demonstrated favorable characteristics such as good foam stability, detergency, and cleansing properties, with ideal physico-chemical evaluation results for stability, safety, and efficacy.
1 citations
,
December 2022 in “Research journal of topical and cosmetic sciences” This study evaluated a polyherbal shampoo containing natural ingredients and found it demonstrated good froth stability, cleansing ability, and conditioning activity, but called for further validation of its overall quality.
1 citations
,
October 2021 in “International journal of pharmaceutics and drug analysis” This study found that a herbal shampoo containing Aloe Vera and essential oils performed better in tests for smoothness, shine, and conditioning compared to a marketed shampoo.
March 2026 in “International Journal of Pharmaceutics and Drug Analysis” This study formulated an herbal anti-dandruff shampoo using jackfruit seed extract and evaluated its effectiveness against Malassezia furfur, finding that the fourth formulation exhibited both strong antifungal activity and stability, suggesting a natural alternative to synthetic hair care products.
January 2026 in “Dermatologic Therapy” This study found that a shampoo containing 1% selenium sulfide and 1% salicylic acid significantly improved the clinical signs and symptoms of seborrheic dermatitis and dandruff over an 8-week period.
May 2025 in “Journal of Dermatological Treatment” This study found that a medicated shampoo containing selenium sulfide and salicylic acid effectively reduced symptoms of seborrheic dermatitis in Chinese patients, but females experienced significantly lower rates of good effectiveness and tolerance compared to males.
February 2025 in “Biomimetics” This study developed a novel hair-straightening shampoo incorporating a polyphenol–inorganic sulfate redox agent, finding that it effectively straightens hair while enhancing strength and reducing damage due to its protective polyphenol coating.
January 2025 in “Green energy and technology”
January 2025 in “Journal of Pharmacognosy and Phytochemistry” This study developed an herbal shampoo with Emblica officinalis (amla) and Eclipta alba (bhringraj), known from Ayurvedic medicine, which showed effective cleansing ability and improved hair texture and manageability, suggesting it is a promising chemical-free option for hair care.
January 2025 in “Journal of Pharmacognosy and Phytochemistry” This study developed plant-pigment-based shampoos using extracts from Neem, Fenugreek, Hibiscus, and Butterfly Pea, which demonstrated stability, antimicrobial properties, and potential scalp benefits such as hair growth promotion and dandruff reduction, making them a promising alternative to synthetic dyes.
May 2024 in “Journal of cosmetic dermatology” This study found that while caffeine and adenosine can inhibit hair loss and stimulate hair growth, more research is needed to fully understand the efficacy of shampoo formulations containing specific proportions of these compounds for hair loss treatment and prevention.
January 2024 in “Open Journal of Veterinary Medicine” In this study on dogs with yeast imbalances and dermatological signs, a protocol using chlorhexidine and Ophytrium products significantly reduced Malassezia pachydermatis counts and improved pruritus and irritation scores over 21 days, earning positive assessments from veterinarians and owners in most cases.
March 2023 in “International journal of biology, pharmacy and allied sciences” This study developed a herbal shampoo using fermented oryza sativa water and natural ingredients like amla and aloe vera, reporting that it effectively removes sebum, filth, and dandruff while promoting hair growth and strengthening.
October 2022 in “Journal of the American Academy of Dermatology” This study found that "clean" shampoos are less likely to contain allergenic preservatives compared to traditional shampoos, but both types use fragrance equally, which can be irritating or allergenic.
September 2022 in “International journal of pharmaceutical quality assurance” This study concluded that sodium lauryl sulfate is very toxic to hair, damaging its structure, while natural conditioners help protect hair integrity and improve consistency and shine.
February 2022 in “Journal of pharmaceutical research international” In this study, a herbal shampoo was formulated with ingredients such as neem, hibiscus, and aloe vera, aimed at promoting hair growth, reducing dandruff, and enhancing hair strength; the shampoo was evaluated for its physical and chemical stability.
November 2016 in “University of the Arts London Research Online (University of the Arts London)” This study concluded that adding polymeric conditioning actives to shampoos improved color retention in permanently dyed hair, while additional cationic dyes at certain pH levels weakly dyed the hair directly.
35 citations
,
April 1956 in “Journal of the American Medical Association” This study found that using selenium sulfide shampoo for seborrheic dermatitis was associated with hair loss, which ceased after discontinuing the shampoo.
26 citations
,
December 2009 in “Laser Physics” This study observed that caffeine-containing shampoo can penetrate hair follicles to a depth of approximately 200 μm and remains detectable even after 24 hours, suggesting a potential long-term reservoir effect.