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This study explored the mechanism of Shaoyao Gancao decoction in treating alopecia areata and found that it may be closely related to the PI3K/AKT signaling pathway.

This study found that sebaceous glands in the skin are primarily renewed by their own stem cells during normal conditions, but after injury, they regenerate through stem cells from hair follicles, highlighting stem cell plasticity and regeneration capabilities.

This review identifies sebaceous gland disorders as key indicators of hormonal imbalances, detailing how various hormones affect sebaceous function, and emphasizes a multidisciplinary approach to improve diagnosis and management by integrating endocrine, metabolic, and dermatologic insights.

This discussion reviews the shift in pharmaceutical strategy towards evidence-based and structure-guided drug development, highlighting ongoing challenges and efforts in computer-aided drug design without presenting new clinical results.

In this study, BLIMP1 was found to function in terminally differentiated epidermal cells to maintain homeostasis, rather than defining a sebocyte progenitor population.

This study found that JunB, a transcription factor, is crucial for maintaining epidermal-pilosebaceous stem cell homeostasis by regulating progenitor cell behavior and preventing sebaceous gland dysfunction.

This study found that in mouse skin, the activation of stem/progenitor cells is synchronized across different niches during growth, with the glutamate transporter SLC1A3 playing a crucial role in this process.

The study suggests that abnormal activation of hair follicle stem cells and Wnt10b/β-catenin signaling may contribute to the development of sebaceous neoplasms.

This study found that activin B promotes the initiation and development of hair follicles in both cultured and neonatal mouse skin models.

This review discusses the isolation, structure, and bioactivity of lignans and neolignans from 2016 to mid-2018, reporting no new clinical results but highlighting their potential protective properties against diseases such as cancer and neurodegeneration.

This review discusses idiopathic hirsutism, potential underlying mechanisms, and various therapeutic approaches without providing new clinical results, and emphasizes the need for further research on well-defined patient groups.

Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.

This article reviews the clinical presentation, contributing factors, and prevalence of polycystic ovary syndrome but provides no original research findings.

This study identified a new gene, mrp4, in mice, which suggests it may have a unique role in the growth and development of hair follicles in the ears and tails.

This study demonstrated that dermal papilla cells are molecularly distinct from fibroblasts and identified many novel molecules, including a new member of the CTGF protein family.

This study found that regio-specific hydroxylation of cyclosporine A in Sebekia benihana is mediated by the cytochrome P450 hydroxylase CYP-sb21, suggesting potential biotechnological applications for hair growth promotion without immunosuppressive effects.

This review discusses the design and advances of lipid–polymer hybrid nanoparticles as promising delivery systems for genome editing strategies, highlighting their potential in biomedical applications.

This article presents guidelines developed by a multidisciplinary expert panel for the care of adolescent transgender and non-binary individuals with gender dysphoria, emphasizing individualized, affirmative care to enhance well-being and quality of life.

This thesis presents research conducted in partial fulfillment of a Master's degree in Software Systems Engineering but does not report new empirical findings.

In this study, researchers evaluated deep learning methods for diagnosing Alopecia Areata and found that a modified Inception-Resnet-v2 model achieved a high validation accuracy of 97.94% and loss of 10.4%, suggesting it as an effective tool for classifying alopecia-affected hair.

This review discusses the lack of explicit theoretical foundations in empirical studies on transgender men and emphasizes the need for bioethical frameworks to guide decision-making.

This study found that a collaborative care model in rheumatoid arthritis clinics improved nb-DMARD dose optimization, adherence to monitoring guidelines, and detection of related adverse drug events compared to standard care.

This study suggests that low-dose radiotherapy may lead to temporary neurological improvements in some Alzheimer's patients, with 20% showing cognitive improvement at 6 months; it was well-tolerated, though larger trials are needed for confirmation.

This narrative systematic review reports that gel-based, cryogel, and silicone-based cooling caps offer cost-effective and environmentally sustainable alternatives to traditional machine-operated systems for preventing chemotherapy-induced hair loss, particularly benefiting low-income and low-resource settings.

In this study, the integration of obesity-related features and machine learning techniques significantly enhanced cardiovascular disease detection, with the XGBoost classifier achieving a 74% accuracy rate and improved metrics compared to other models.

This study developed a model for detecting sparse hair clusters using enhanced object detection neural networks and medical images, which accurately identifies and counts sparse hair clusters with greater accuracy and efficiency than existing methods.

This review investigates molecular mechanisms behind PCOS pathogenesis and discusses potential therapies, but reports no new clinical results.

This study observed that applying a cream containing secretome from Bovine Umbilical Vein Endothelial Cells promoted healing and regeneration in burn wounds in rats, particularly at a 15% concentration.

This study found that self-supervised pretraining significantly improves accuracy in medical image classifiers for dermatology and chest X-ray tasks, outperforming supervised baselines and showing robustness to distribution shifts with limited labeled data.

In this study, peptide-based nanoparticles were successfully used to deliver the CRISPR-Cas9 system into cancer cells, effectively targeting and editing KRAS mutations, suggesting promising therapeutic potential for cancer treatment.