19 citations,
March 2021 in “Experimental dermatology” Stem cells are key for the growth, upkeep, and repair of sebaceous glands and for understanding skin disorders.
December 2022 in “Molecular Pharmaceutics” Latanoprost-loaded nanotransfersomes could help treat hair loss by promoting hair growth.
October 2023 in “Biomedical science and engineering” Innovative methods are reducing animal testing and improving biomedical research.
119 citations,
March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
12 citations,
September 2020 in “Stem cell research & therapy” Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
Type II spiral ganglion neurites avoid high concentrations of laminin and fibronectin.
18 citations,
April 2014 in “Stem cells” The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
33 citations,
September 2016 in “British journal of dermatology/British journal of dermatology, Supplement” Human hair follicle dermal cells can effectively replace other cells in engineered skin.
10 citations,
September 2022 in “Advanced Healthcare Materials” Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
April 2024 in “Research Square (Research Square)” MSC-protein helps regenerate gum tissue and bone.
56 citations,
September 2013 in “Experimental Dermatology” The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.
4 citations,
November 2021 in “Frontiers in Cell and Developmental Biology” Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.
4 citations,
December 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.
211 citations,
October 2001 in “The FASEB Journal” Noggin is necessary to start the hair growth phase in skin after birth.
96 citations,
October 2000 in “The FASEB Journal” The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
71 citations,
June 2001 in “American Journal of Pathology” The p53 protein helps control hair follicle shrinking by promoting cell death in mice.
21 citations,
March 2019 in “Critical Reviews in Clinical Laboratory Sciences” The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
April 2023 in “Medizinische Genetik” New research has found 14 genes linked to the risk of developing alopecia areata, improving understanding and treatment options.
21 citations,
May 2022 in “Frontiers in Cell and Developmental Biology” Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.
43 citations,
December 2006 in “The American journal of pathology” Edar signaling is crucial for controlling hair growth and regression.
Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.
65 citations,
November 2012 in “Tissue Engineering Part B-reviews” Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
69 citations,
June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
759 citations,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
30 citations,
April 2018 in “Experimental Dermatology” The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
97 citations,
September 2016 in “Reviews in Endocrine and Metabolic Disorders” The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
29 citations,
March 2019 in “British Journal of Dermatology” Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
107 citations,
August 2012 in “Seminars in Cell & Developmental Biology” The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
262 citations,
May 2017 in “Nanomedicine” New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.