research Locally Synthesized 17-Beta-Estradiol Reverses Amyloid-Beta-42-Induced Hippocampal Long-Term Potentiation Deficits
A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.
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research Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study
Eriocitrin and silymarin might be effective for hair loss treatment and need more research.
research Central Precocious Puberty Secondary to Peripheral Precocious Puberty Due to a Pineal Germ Cell Tumor: A Case and Review of Literature
A pineal tumor caused a boy's early puberty, which changed from peripheral to central after treatment.
research The Impact of Androgenic Alopecia on the Quality of Life of Male Individuals: A Cross-Sectional Study
Hair loss significantly lowers life quality, especially in young men, with most patients unhappy with treatment effectiveness.
research Innovative Reports on the Effects of Anabolic Androgenic Steroid Abuse - How to Lose Your Mind for the Love of Sport
Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.
research Matrisomal Components Involved in Regenerative Wound Healing in Axolotl and Acomys: Implications for Biomaterial Development
Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.
research Addressing Autoimmune and Immune-Mediated Skin Disease Burden in Women
The conclusion is that women are heavily affected by autoimmune skin diseases, face significant challenges, and need better research, treatments, and healthcare policies.
research Topical Effect of Minoxidil Containing Lotion on Morphofunctional Indicators of Male Rats’ Reproductive System
Minoxidil lotion may harm male reproductive health.
research The Biological Actions of Dehydroepiandrosterone Involve Multiple Receptors
DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
research A Mouse Model for the Basal Transcription and DNA Repair Syndrome Trichothiodystrophy
Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
research Intracrine Androgen Biosynthesis, Metabolism, and Action Revisited
The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
research Phytochemistry, Pharmacological Activity, And Potential Health Benefits Of Glycyrrhiza Glabra
Licorice has many health benefits but should be used carefully due to possible side effects.
research Advances in Chitosan-Based Nanoparticles for Drug Delivery
Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
research Testosterone in COVID-19: An Adversary Bane or Comrade Boon
Testosterone's effects on COVID-19 are unclear and need more research.
research Principles of Chemotherapy
Chemotherapy is crucial for treating gynecological cancers but requires careful management due to severe side effects.
research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin
Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
research A Comprehensive Review of Acne Vulgaris
Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
research Activation of Extrasynaptic δ-GABAA Receptors Globally or Within the Posterior VTA Has Estrous-Dependent Effects on Alcohol Consumption and Estrous-Independent Effects on Locomotion
δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.
research Assessment of Prescribing Information for Generic Drugs Manufactured in the Middle East and Marketed in Saudi Arabia
Generic drug inserts in Saudi Arabia often have inaccurate information, needing better regulation and quality control.
research Perspectives on MicroRNAs Targeting DKK1 for Developing Hair Regeneration Therapy
Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.
research Polycystic Ovary Syndrome: A Common Reproductive Syndrome with Long-Term Metabolic Consequences
Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.
research Expanding on the Phenotypic Spectrum of Woodhouse-Sakati Syndrome Due to Founder Pathogenic Variant in DCAF17: Report of 58 Additional Patients from Qatar and Literature Review
Woodhouse-Sakati syndrome shows varied symptoms, including hair loss and diabetes, and is common in Qatar due to a specific genetic variant.
research Regenerative Medicine Strategies for Hair Growth and Regeneration: A Narrative Review of Literature
New regenerative treatments for hair loss show promise but need more research for confirmation.
research Complex X Chromosome Rearrangement Associated with Multiorgan Autoimmunity
A complex X chromosome rearrangement can increase the risk of multiple autoimmune diseases.
research Quercetin and Polycystic Ovary Syndrome
Quercetin may help improve symptoms of polycystic ovary syndrome.
research Regulation of Stem Cell Fate by HSPGs: Implication in Hair Follicle Cycling
HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.
research Hair Microscopy: An Easy Adjunct to Diagnosis of Systemic Diseases in Children
Hair microscopy is a simple and cost-effective method to help diagnose systemic diseases in children.
research Short-Term Efficacy of Autologous Cellular Micrografts in Male and Female Androgenetic Alopecia: A Retrospective Cohort Study
Autologous cellular micrografts improve hair density and thickness in the short term for androgenetic alopecia.
research Pregnenolone for the Treatment of L-DOPA-Induced Dyskinesia in Parkinson's Disease
Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.
research Adipose-Derived Stem Cells in Skin Diseases, Wound Healing, and Skin Defects: A Review
Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.