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Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Vitiligo affects overall health and self-esteem, needing more research and awareness.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Scientists found a gene in mice that causes early hearing loss.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

The article suggests using four questions to tell apart necessary medicalization from excessive medicalization, focusing on problem significance, social expectations, medical understanding, and effective resolution.

Finasteride may help reduce symptoms in male Tourette syndrome patients.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Spironolactone might help protect against severe lung problems in COVID-19 patients.