December 2018 in “Actas urológicas españolas” 5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.
April 2016 in “Journal of The American Academy of Dermatology” Dutasteride works better than finasteride for hair growth with similar side effects.
April 2016 in “Journal of The American Academy of Dermatology” Dutasteride is more effective than finasteride for hair growth with similar side effects.
The article concludes that understanding the causes of hair loss and using continuous treatments like minoxidil and finasteride can help manage it, despite potential side effects.
Traditional Chinese Medicine, combined with antiandrogen therapy, could improve treatment and reduce side effects for genetic hair loss.
July 2012 in “The Journal of Urology” Testosterone increases muscle mass regardless of DHT conversion blocking.
October 2010 in “Journal of Men's Health” The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.
November 2022 in “Cureus” New biomaterial treatments for baldness show promise, with options depending on patient needs.
April 2022 in “The Journal of Sexual Medicine” Finasteride alone increases suicide risk, but combining it with other treatments reduces this risk.
May 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Clinicians need to better understand and treat Post-finasteride syndrome.
December 2017 in “Huisarts En Wetenschap” Finasteride helps hair growth in early male baldness, but more long-term research needed.
November 2016 in “Hair transplant forum international” The conclusion is that more research is needed to understand if the drug finasteride causes Post-Finasteride Syndrome or if it's due to individual genetic makeup.
March 2016 in “Reactions Weekly” Post-finasteride syndrome causes various symptoms in men using finasteride, with no known cure.
April 2015 in “Reactions Weekly” Finasteride toxicity information is limited, poor quality, and biased.
January 2011 in “Journal of biological research” Endocrine disruptors may cause early hair loss.
November 2003 in “Journal of Dermatology” Finasteride's link to depression is questionable due to study flaws and potential bias.
282 citations,
October 2006 in “The Journal of Clinical Endocrinology and Metabolism” The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
76 citations,
November 1997 in “The American journal of psychiatry” Some autistic children may have higher levels of male hormones, which could be linked to aggression.
39 citations,
April 2018 in “Hormones” No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.
23 citations,
January 2003 in “Journal of Pediatric Endocrinology and Metabolism” About 15% of US Army personnel use hair products containing hormone or placenta, with higher usage among non-whites, females, and enlisted personnel.
5 citations,
January 2001 in “Advances in protein chemistry” 5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.
1 citations,
July 2018 in “Current Sexual Health Reports” Post-finasteride Syndrome causes lasting negative effects, but more research is needed for treatment and risk evaluation.
1 citations,
April 2006 in “Seminars in Reproductive Medicine” Androgen therapy might help some women with low libido, but it has risks and should be used carefully.
September 2023 in “Fides et Ratio” The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.
October 2022 in “Medical Clinical Update Journal” Early diagnosis and treatment with Leuprolide are key for children with precocious puberty.
May 2019 in “The Journal of Sexual Medicine” Drinking alcohol before taking flibanserin does not increase the risk of severe low blood pressure or fainting.
February 2021 in “The Brown University Psychopharmacology Update” Finasteride use in young people may increase risk of suicidal thoughts and mental health issues.
November 2020 in “Reactions Weekly” Finasteride use linked to increased suicidality in patients under 45.
204 citations,
May 2014 in “The Journal of Sexual Medicine” Hormone therapy for trans individuals is effective and generally safe in the short term.
29 citations,
July 2012 in “The Journal of Sexual Medicine” Rats had lasting erectile problems after stopping a certain medication.