research Risk of Depression After 5 Alpha Reductase Inhibitor Medication: Meta-Analysis
Taking 5 alpha reductase inhibitor medication slightly increases the risk of depression, especially as you get older.
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research Evaluation of Dutasteride-Loaded Liposomes and Transfersomes for Follicular Targeting in Androgenic Alopecia Topical Treatment
Transfersomes are better than liposomes for targeting hair follicles in alopecia treatment.
research Is Semen Analysis Necessary Prior to Initiation of Finasteride Treatment?
research Hormonal Manipulation of Benign Prostatic Hyperplasia
Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.
research Recent Advances in Understanding of the Etiopathogenesis, Diagnosis, and Management of Hair Loss Diseases
New understanding and treatments for hair loss are improving, but more research is needed.
research Proceedings of the Ninth World Congress for Hair Research 2015
The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
research Finasteride
research A Gender Hypothesis of Sex Disparities in Adverse Drug Events
Gendered social factors, not just biology, contribute to sex differences in adverse drug events.
research Efficacy and Safety of 5 Alpha-Reductase Inhibitor Monotherapy in Patients with Benign Prostatic Hyperplasia: A Meta-Analysis
5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.
research Assessing Dutasteride-Associated Sexual Dysfunction Using the U.S. Food and Drug Administration Adverse Event Reporting System
Dutasteride is linked to a higher chance of sexual dysfunction, especially in younger males and the elderly.
research Persistent Sexual Dysfunction and Suicidal Ideation in Young Men Treated with Low-Dose Finasteride: A Pharmacovigilance Study
Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.
research Topical Solutions for Androgenetic Alopecia: Evaluating Efficacy and Safety
Topical treatments for hair loss can be effective but need careful safety evaluation.
research Long-Term Effectiveness and Safety of Dutasteride Versus Finasteride in Patients With Male Androgenic Alopecia in South Korea: A Multicentre Chart Review Study
Dutasteride is more effective than finasteride for long-term hair growth in men with androgenic alopecia.
research The Hydroxypropyl-β-Cyclodextrin-Minoxidil Inclusion Complex Improves the Cardiovascular and Proliferative Adverse Effects of Minoxidil in Male Rats: Implications in the Treatment of Alopecia
A new gel form of minoxidil is equally effective for hair growth and safer for the heart and other organs than the traditional solution.
research Penile Vascular Abnormalities in Young Men with Persistent Side Effects After Finasteride Use for the Treatment of Androgenic Alopecia
Finasteride for hair loss may cause lasting sexual, genitourinary, mental, and anti-androgenic side effects in young men.
research Disproportional Signal of Sexual Dysfunction Reports Associated with Finasteride Use in Young Men with Androgenetic Alopecia: A Pharmacovigilance Analysis of VigiBase
Finasteride use in young men with hair loss is linked to sexual dysfunction.
research Adverse Effects of 5-Alpha-Reductase Inhibitors: A Narrative Review
5-Alpha-Reductase Inhibitors can cause negative side effects.
research Diagnostic Criteria for Enduring Sexual Dysfunction After Treatment With Antidepressants, Finasteride, and Isotretinoin
The document sets criteria for diagnosing long-term sexual dysfunctions caused by certain medications.
research Evaluating 5 Alpha Reductase Inhibitors for the Treatment of Male Androgenic Alopecia
Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.
research Finasteride Induced Gynecomastia: Case Report and Review of the Literature
Finasteride for hair loss may cause gynecomastia; doctors should inform patients.
research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders
S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
research Inhibitors of 5α-Reductase in the Treatment of Benign Prostatic Hyperplasia
5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.
research The Role of Topical Finasteride in Hair Loss Management: Current Evidence and Future Perspectives
Topical finasteride might help with male hair loss with fewer side effects than pills, but more research is needed.
research Post-Finasteride Syndrome
research Exploring the Mechanisms and Molecular Targets of Taohong Siwu Decoction for the Treatment of Androgenetic Alopecia Based on Network Analysis and Molecular Docking
Taohong Siwu Decoction may help treat hair loss by targeting multiple genes and pathways.
research Comparative Effects of Finasteride and Minoxidil on Male Reproductive Organs: A Systematic Review of In Vitro and In Vivo Evidence
Finasteride is more harmful to male reproductive health than minoxidil.
research Pediatric Androgenetic Alopecia: An Updated Review
Early diagnosis and personalized treatment are crucial for managing hair loss in children.
research Testosterone Therapy for Sexual Dysfunction in Postmenopausal Women
Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.
research Efficacy, Safety, and Tolerability of Dutasteride 0.5 mg Once Daily in Male Patients with Male Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase III Study
Dutasteride 0.5 mg daily improves hair growth safely in men with hair loss.
research Evaluation of Risk of SSRI-Associated Impotence and Low Libido in Men Exposed to Finasteride
Finasteride and SSRIs together increase impotence and low libido risk in men.