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A young man with an eating disorder had a life-threatening adrenal crisis due to an autoimmune condition, highlighting the need for better education on managing hormone treatments.

The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Melatonin may help manage PCOS by improving insulin sensitivity, hormone balance, and mood.

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.

Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.

Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.

New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.

Anabolic steroid users may face higher risk of severe COVID-19.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

People with androgenetic alopecia, both men and women, are more likely to develop heart diseases in the future.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.

The conclusion is that thorough investigation of hypertension and hormonal dysfunctions is important, and there may be a link between these conditions and cancer.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

New treatments and diagnostic methods for various animal skin conditions showed promising results.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Adrenal disorders can cause lasting brain and behavior issues in children.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.