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Blocking JAK-STAT5 signaling in mice leads to hair growth.

The Leechbook shows how hair and sexual health were key to medieval masculinity and some remedies may still be useful.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Fat cells help recruit healing cells and build skin structure during wound healing.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Lactate production is important for activating hair growth stem cells.

Oestrogens are key for bone growth during puberty in both boys and girls.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.