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Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Fibroblast Growth Factor-9 (FGF-9) can help improve heart function in diabetic mice after a heart attack by reducing inflammation and harmful changes to the heart's structure.

Different STUB1 gene mutations cause varied symptoms in autosomal recessive ataxias.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

Women with scarring alopecia are less likely to have used hormone replacement therapy or oral contraceptives compared to those with female pattern hair loss.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Selective breeding caused the unique curly hair in Mangalitza pigs.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

Thyroid problems are linked to various skin issues, and checking thyroid health is important for people with certain skin conditions.

MRI helps distinguish between pituitary adenomas and craniopharyngiomas, guides treatment for pediatric CNS tumors, and assesses rhinocerebral mucormycosis with a high mortality rate in transplanted patients.

People with alopecia areata often have lower levels of zinc and vitamin D.

Cross-section trichometry is an accurate method to measure hair loss and growth.

Certain gene variations may increase the risk of alopecia, and platelet-rich plasma treatment can improve hair density in those with hair loss; a rare case of facial Becker's nevus was linked to uneven beard growth.

Certain gene variations might increase the risk of a hair loss condition in Koreans.

Adult hair follicle cells can create new hair follicles from corneal cells with the right support.

Growth factors are crucial for hair development and could help treat hair diseases.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

A gene variation is linked to hair thickness in Asians.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

The document concludes that individualized Facial Feminization Surgery plans and comprehensive care are crucial for successful outcomes.

Low ferritin levels can indicate iron deficiency as a cause of hair loss.

People with pattern hair loss have higher polyamine levels in the top of their head compared to the back.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.