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Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

People with hair loss have higher risk of high blood sugar and diabetes, and lower levels of a specific hormone.

Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Sex hormones affect brain injury differently in males and females.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

Male cancer patients have a higher risk of severe illness and death from COVID-19 than female patients.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Skin problems can be linked to sexual abuse, requiring careful medical and psychological evaluation.

Cross-sex hormone treatment in transsexual individuals helps understand how sex hormones affect diseases like heart disease and diabetes.

SHBG binding properties are unchanged in male liver cirrhosis patients.

Men with hair loss have lower SHBG and higher saliva testosterone levels, suggesting increased androgen activity.

Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Finasteride use linked to increased risk of sexual dysfunction, especially in younger people.

Finasteride can cause sexual problems and depression in young men.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Hormones and sex affect potassium channel gene expression in electric fish, influencing their communication signals.

Finasteride and dutasteride can cause sexual problems like impotence and low libido.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

No link found between specific genes and female pattern hair loss.

Higher androgen levels do not cause baldness in men.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.