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Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Women with persistent acne and high levels of antimullerian hormone are more likely to have polycystic ovarian syndrome.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

Testosterone reduces key molecules needed for early pregnancy in rats.

High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.

Early hormones shape sex-specific differences in rat glands.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Age, smoking, and lower BMI increase facial wrinkles; men wrinkle more than women, except in old age; pale skin and certain hormonal factors can protect against wrinkles.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Many COVID-19 patients have long-term symptoms, especially women, but certain medications may help reduce these symptoms.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

Gut microbes significantly affect brain steroid levels.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.