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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.

RU 58841 may treat acne, hair loss, and excessive hair growth.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Men who start losing hair at age 30 may have a lower risk of prostate cancer.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

People with androgenetic alopecia, both men and women, are more likely to develop heart diseases in the future.

More research is needed to understand how testosterone is maintained in adult males.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Anabolic steroid users may face higher risk of severe COVID-19.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

New treatments and diagnostic methods for various animal skin conditions showed promising results.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.