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PCOS affects nearly 25% of female medical and dental students, impacting their academic and social lives.

A postmenopausal woman's excess male hormone symptoms improved after her ovaries were removed.

Polycystic ovary syndrome causes high male hormone levels, leading to symptoms like excess hair, acne, and fertility problems.

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.

5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

Certain existing drugs, like glycopyrronium and botulinum toxin type A, may help treat excessive sweating.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

Quercetin may help improve symptoms of polycystic ovary syndrome.

Removing a testosterone-producing tumor cured a woman's sleep apnea and other symptoms.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.

Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

Women with Polycystic Ovary Syndrome are more likely to have Non-Alcoholic Fatty Pancreas Disease, which is associated with older age, metabolic syndrome, insulin resistance, and high male hormone levels.

Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

GnRH analogue can help diagnose ovarian causes of high testosterone in postmenopausal women when scans don't show the cause.

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

Cyproterone Acetate effectively treats androgen-related conditions and is used in prostate cancer therapy and hormone therapy for transgender women.

PCOS is often caused by hormonal imbalances that can lead to various health issues and may indicate a risk for future metabolic and cardiovascular problems.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.

MAIT cells may help fight COVID-19 but also contribute to severe inflammation.

Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Long COVID affects over half of COVID-19 survivors, causing a range of symptoms like fatigue and neurological issues, with no specific treatment yet.