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This case report details severe hematological toxicity and fatal complications from azathioprine in a patient with Crohn's disease with a homozygous NUDT 15 variant, suggesting pharmacogenomic testing before treatment.

This case report describes a 4-month-old child with symptoms suggesting multiple carboxylase deficiency, which responded well to biotin therapy, highlighting the importance of early diagnosis and treatment to prevent serious health issues in infants with similar unexplained metabolic acidosis and symptoms.

This research investigated the role of EphA1 in embryonic and adult tissues, generating mouse models suggesting potential links to skin and colon cancer, sepsis, and post-traumatic injury.

In this study, a patient with Cronkhite-Canada syndrome complicated by severe sepsis and disseminated intravascular coagulation was successfully treated using combined therapies, including recombinant human soluble thrombomodulin, despite the absence of a standard treatment regimen for CCS.

This case report describes a rare occurrence of primary cutaneous diffuse large B-cell lymphoma, not otherwise specified (PCDLBCL-NOS) on the scalp of a 45-year-old female, highlighting its unusual presentation and the initial treatment response but also noting severe subsequent complications.

In this case report, a 7-month-old girl with suspected acrodermatitis enteropathica and severe dermatitis experienced a tragic outcome despite zinc treatment, highlighting the challenges of diagnosing and managing this rare genetic disorder.

This case report describes group A streptococcal septicemia with monoarticular arthritis linked to an infected IUD, likely transmitted through sexual foreplay in a 28-year-old woman.

This case report describes an 8-year-old boy with acrodermatitis enteropathica who showed significant recovery from severe symptoms after receiving a therapeutic zinc supplement.

This case report highlights that in severe illnesses like sepsis, myxedema coma can occur with less elevated TSH levels than typical for primary hypothyroidism, likely due to inflammatory cytokines affecting TSH secretion, even when central lesions are absent.

This report describes a Cronkhite-Canada syndrome patient with severe sepsis and disseminated intravascular coagulation successfully treated using combined therapies, including recombinant human soluble thrombomodulin.

This article explains the characteristics, diagnosis, and causes of telogen effluvium hair loss but reports no new clinical findings.

This study reports a case of a patient with neuromyelitis optica spectrum disorders treated with eculizumab who developed fatal sepsis after insulin resistance emerged.

This case report describes a 36-year-old woman with hidradenitis suppurativa whose condition progressed to rapidly fatal squamous cell carcinoma, highlighting the potential for aggressive tumor development linked to specific protein markers.

This case series highlights severe micronutrient deficiencies and complications in three patients who did not adhere to follow-up care after Roux-en-Y gastric bypass, emphasizing the importance of regular nutritional monitoring.

This manuscript describes two case reports of preterm newborns with a rare homozygous mutation in the epidermal growth factor receptor, leading to severe health issues and early mortality despite supportive care.

This case report of an infant with IPEX syndrome highlights the importance of early recognition and treatment, as the patient experienced severe symptoms and succumbed before stem cell transplantation.

This review assessed the potential of mesenchymal stem cell therapy to enhance burn wound healing, highlighting its capabilities in promoting angiogenesis, reducing inflammation, and regenerating damaged tissues, while identifying preclinical and clinical challenges that need addressing to optimize treatment outcomes.

This article reviews Netherton syndrome, focusing on its genetic basis, clinical presentation, and treatment options, and reports no clinical results; the authors mention potential benefits of targeted therapies and gene therapy.

This review discusses the diagnosis and management of severe cutaneous adverse reactions to drugs and provides guidance for physicians to improve patient outcomes, but it reports no new clinical results.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

A boy with toxic shock syndrome had severe heart rhythm problems but recovered with treatment.

This study found that in a small cohort of patients with infections, tumor necrosis factor levels varied, challenging the interpretation that these levels are transient in gram-negative sepsis.

This article is a case report on severe hair loss due to telogen effluvium occurring during inpatient rehabilitation and does not provide new clinical results.

This report describes a rare case of severe combined immunodeficiency caused by a FOXN1 gene variant, complicated by Epstein-Barr virus infection and high-grade B-cell lymphoma, leading to the infant's death despite treatment efforts.

This study suggests that finasteride treatment may improve pulmonary immune response in mice following trauma and sepsis, indicating potential as a therapeutic option after major trauma.

This case study reports a new LAMB3 mutation linked to junctional epidermolysis bullosa with severe urinary tract stenosis, outlining treatment challenges and expanding knowledge of EB-related urological complications.

This study found that a single dose of 1 mg/kg dexamethasone promoted wound healing in septic mice but delayed it in normal mice.

Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.

Combination antibiotic therapy is more effective but causes more side effects.

This review discusses adverse cutaneous drug reactions associated with antidepressants and provides guidance on managing these reactions, but it reports no new clinical findings; the authors recommend cautious use and alternative treatment if reactions occur.