research Nail Involvement in Patients with Moderate-to-Severe Alopecia Areata Treated with Oral Tofacitinib
Tofacitinib improves nail conditions in patients with severe hair loss and does not affect hair regrowth.
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research A Randomized Placebo-Controlled Single-Center Pilot Study of the Safety and Efficacy of Apremilast in Subjects with Moderate-to-Severe Alopecia Areata
Apremilast was not effective in treating moderate-to-severe alopecia areata.
research Combination Therapy with Cyclosporine and Psoralen Plus Ultraviolet A in Patients with Severe Alopecia Areata: A Retrospective Study with a Self-Controlled Design
The combination of cyclosporine and PUVA might help treat severe alopecia areata.
research Sequential High- And Low-Dose Systemic Corticosteroid Therapy For Severe Childhood Alopecia Areata
High and low doses of prednisolone helped 62% of children with severe alopecia regrow hair with some weight gain and mild acne as side effects.
research Improvement in Measures of Quality of Life and Symptoms of Anxiety and Depression in Patients with Severe Alopecia Areata Achieving Sustained Scalp Hair Regrowth with Baricitinib
Baricitinib improves quality of life and reduces anxiety and depression in severe alopecia areata patients with hair regrowth.
research Comparative Efficacy and Safety of JAK Inhibitors in the Treatment of Moderate-to-Severe Alopecia Areata: A Systematic Review and Network Meta-Analysis
Brepocitinib 30mg is most effective for moderate-to-severe alopecia areata, but ritlecitinib 50mg may offer a better balance of safety and effectiveness.
research Comparative Efficacy and Adverse Clinical Events of Methotrexate Versus Azathioprine with Steroid Mini Pulse Therapy in the Management of Moderate to Severe Alopecia Areata: A Tertiary Centre Based Interventional Study
Methotrexate with steroids is slightly more effective than azathioprine with steroids for treating severe alopecia areata.
research Capillaroscopic Patterns in Patients with Systemic Sclerosis, Psoriasis, and Alopecia and Their Correlations with Serum Concentrations of Several Angiogenic Markers
Blood vessel patterns in skin diseases relate to certain blood markers in systemic sclerosis but not in psoriasis or psoriatic arthritis, and may indicate circulation issues in alopecia.
research Disease Burden, Clinical Management, and Unmet Treatment Need of Patients With Moderate to Severe Alopecia Areata: Consensus Statements, Insights, and Practices From CERTAAE Delphi Panel
Alopecia Areata significantly lowers quality of life and current treatments are inadequate, highlighting a need for better therapies and standardized treatment protocols.
research Can Platelet-Rich Plasma Reduce the Burden of Inflammatory Skin Diseases Such as Psoriasis and Atopic Dermatitis?
Platelet-rich plasma treatment may safely and effectively reduce skin lesions in psoriasis and atopic dermatitis.
research Impact of Clinical Severity on Absenteeism and Presenteeism in Patients with Hidradenitis Suppurativa
Severe Hidradenitis Suppurativa increases missed and unproductive workdays.
research Egr-1 Is Main Key Regulator in IL-17F-Induced Psoriasin Expression in Human Keratinocytes
Psoriasis is linked to a higher risk of autoimmune diseases and other health conditions.
research Efficacy and Safety of Tofacitinib Therapy in Asian Patients with Severe Alopecia Areata
Tofacitinib helps regrow hair in severe alopecia patients, but more research is needed.
research Efficacy and Safety of Topical Rosuvastatin and Melatonin vs. Placebo in Patients with Mild to Moderate Plaque Psoriasis: A Preliminary Randomized Double-Blinded Clinical Trial
Topical rosuvastatin and melatonin creams significantly reduce psoriasis severity and are safe.
research Severe Androgenetic Alopecia as a Marker of Metabolic Syndrome in Male Patients: A Hospital-Based Case Control Study
Men with severe hair loss are more likely to have metabolic syndrome, a condition linked to heart disease.
research Identification of Distinct Immune Signatures and Chemokine Networks in Scalp Inflammatory Diseases
Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.
research Association of Demographic and Hospital Characteristics with Emergency Department Visits Due to Sunburn
Young, lower-income men are more likely to visit the emergency department for severe sunburns, especially in the summer and on weekends.
research Vitamin D and the Skin: Focus on a Complex Relationship
Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.
research Dermatologic Changes Associated With Interleukin 2 Administration
IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.
research Immunologic Adverse Reactions of Beta-Blockers and the Skin: A Review
β-blockers can cause skin problems like psoriasis and vitiligo, and doctors should tell patients about these risks.
research Keratin and Skin Disorders
Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
research Skin Manifestations Associated with Autoimmune Liver Diseases: A Systematic Review
Autoimmune liver diseases are likely linked to certain skin conditions like vitiligo and psoriasis.
research Acne Induced by 'Sus' and 'Deca'
Using anabolic steroids 'Sus' and 'Deca' for bodybuilding caused severe acne in a man.
research Summaries of Papers
The document concludes that secondary syphilis cases are increasing and often misdiagnosed, pityriasis rubra pilaris can be distinguished from psoriasis by skin cell features, and different skin layers produce specific components during skin repair.
research Low-Level Laser Therapy in Immune-Mediated Skin Disease: A Narrative Review
Low-level laser therapy may help with hair regrowth in alopecia areata but its effectiveness for psoriasis and atopic dermatitis needs more research.
research Increased Prevalence of Bipolar Disorders in Hidradenitis Suppurativa: More Than a Striking Coexistence?
People with hidradenitis suppurativa are more likely to have bipolar disorder than those with psoriasis or without skin conditions.
research Cross-Sectional Evaluation of Cutaneous Manifestations Associated with Chronic Alcoholism
More frequent and severe skin problems are linked to higher daily alcohol consumption.
research Case Report: Alopecia Areata and Cannabis Use
A girl with severe hair loss saw hair regrowth after using cannabis.
research Extensive Alopecia Areata Is Reversed by IL-12/IL-23p40 Cytokine Antagonism
Blocking IL-12/IL-23p40 helped reverse severe hair loss in patients.
research Cutaneous Manifestations of HIV Infection Other Than Kaposi's Sarcoma: Clinical and Histologic Aspects
HIV can cause various severe or unusual skin conditions that help indicate the presence and stage of the disease.