March 2024 in “Clinical and experimental dermatology” Topical corticosteroids may be a safe and effective treatment for severe alopecia areata in children.
1 citations,
April 1976 in “Archives of Dermatology” Sudden weight loss can cause significant hair loss, and using colchicine on the skin for psoriasis may be unsafe.
238 citations,
November 2016 in “Journal of The American Academy of Dermatology” Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.
66 citations,
December 2018 in “Dermatology” Both ruxolitinib and tofacitinib are effective and safe for treating severe alopecia areata, but relapses are common.
11 citations,
February 2021 in “Journal of Cosmetic Dermatology” Oral tofacitinib helped regrow hair in over half of the patients with severe alopecia, but relapses and side effects were common.
2 citations,
April 2022 in “Medicine” A Chinese boy's scalp infection from a guinea pig was cured with medication.
November 2024 in “Journal of Cutaneous and Aesthetic Surgery” Combining platelet-rich plasma and minoxidil can effectively regrow hair in severe alopecia areata cases.
1 citations,
October 2023 in “Dermatology and therapy” Some treatments for severe hair loss work but often have side effects, with baricitinib showing the most promise.
14 citations,
January 2011 in “International Journal of Trichology” Some people with severe, long-lasting baldness responded well to a specific combination treatment.
2 citations,
September 2013 in “Journal of Veterinary Internal Medicine” Sweat hypersensitivity can cause severe skin issues in horses.
25 citations,
November 2022 in “British journal of dermatology/British journal of dermatology, Supplement” Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.
1 citations,
April 2019 in “Acta Medica Philippina” Azathioprine may help treat severe alopecia areata, but more research is needed.
98 citations,
March 2019 in “Frontiers in immunology” Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.
1 citations,
January 2020 in “Revista Brasileira de Ciência Veterinária” A cat in Brazil had severe skin issues worsened by improper treatment.
3 citations,
January 2021 in “Therapeutic advances in infectious disease” A 9-year-old girl with a healthy immune system was successfully treated for a severe fungal scalp infection caused by Microsporum audouinii.
2 citations,
January 2023 in “Frontiers in Veterinary Science” Buffalo flies and Stephanofilaria nematodes cause severe skin lesions in beef cattle, and treatment should target both.
3 citations,
August 2010 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” A rare genetic disease caused severe, worsening hair loss from early childhood with poor treatment results.
8 citations,
June 2022 in “Frontiers in Medicine” Both individual and combined treatments of tofacitinib and corticosteroids can help regrow hair in moderate-to-severe alopecia areata, but ongoing treatment may be necessary.
32 citations,
September 2015 in “Dermatology” Certain leukemia drugs can cause severe skin reactions that may require stopping treatment.
278 citations,
May 2013 in “Ca” Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.
6 citations,
April 2012 in “Lasers in surgery and medicine” Laser hair removal can cause a severe itchy rash in some allergic individuals, treatable with steroids.
1 citations,
March 2022 in “Cureus” A woman with lupus and systemic sclerosis developed severe acne that didn't improve with treatment and died from pneumonia and septic shock.
11 citations,
February 2003 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.
June 2023 in “Journal of Cosmetic Dermatology” The new follicular unit extraction treatment effectively treats severe hair loss in Asian men, giving natural-looking results with few side effects.
105 citations,
September 1995 in “Journal of The American Academy of Dermatology” Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.
12 citations,
May 2017 in “Medicine” Oral isotretinoin was recommended for a 21-year-old woman with severe acne.
February 2013 in “Archives of Disease in Childhood: Education & Practice” Different types of alopecia in children require specific diagnoses and treatments.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Some African American women experience central scalp hair loss, often linked to a history of fungal scalp infection.
4 citations,
January 2017 in “Ciência Rural” A horse in Brazil with skin and gut issues was diagnosed with a severe disease and had to be euthanized.