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Polycystic Ovary Syndrome (PCOS) often leads to severe acne, and lifestyle changes and hormonal treatments can help manage it.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

This paper discusses hormonal therapy options for women with severe acne, focusing on treatment for cases that do not respond to conventional methods, but it reports no new clinical findings.

In this study, researchers found that increased androgen levels, such as testosterone, and insulin resistance are strongly associated with more severe acne in adult women, along with a higher incidence of menstrual irregularities and PCOS characteristics.

This study highlights the evolving understanding of acne's pathophysiology and suggests that targeting pro-inflammatory cytokines such as IL-1β, IL-17, IL-23, and TNFα with biological antibodies may offer new treatment strategies for severe acne and its scars.

In this case report, a patient on low-dose sorafenib for hepatocellular carcinoma developed a rare and severe facial acneiform eruption without other skin side effects, which improved only minimally with topical treatment.

In this study, researchers reported that acne is a complex and chronic skin condition most commonly affecting individuals aged 11 to 30, with more severe cases observed more frequently in men and areas rich in sebaceous glands like the face, back, and chest.

Evaluate and manage androgen excess in women with a systematic approach, considering both physical and psychological impacts.

Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.

This review outlines a diagnostic approach for identifying non-PCOS pathology in women with androgen excess, emphasizing the importance of clinical history and biochemical phenotyping but reports no new clinical results.

New acne treatments include combination creams, advanced retinoids, and light therapies, focusing on safety and patient adherence.

Acne in children varies by age and severity, requires a pediatric treatment approach, and may need diagnostic evaluation for underlying conditions.

This book reviews the various types of acne and acneiform conditions, as well as their treatment options, with expert insights from multiple fields.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

The document says that early treatment of Acne Vulgaris is important to prevent scarring and that adult onset acne is common in women, often due to hormonal imbalances.

This article discusses the association of acne with various systemic diseases, emphasizing the role of androgen steroids, insulin resistance, and inflammation in acne pathogenesis, but it reports no new clinical results.

In this study, researchers found no association between the use of oral isotretinoin at a standard dose and the development of milia in patients with moderate-to-severe acne vulgaris.

This article discusses the treatment considerations for a 17-year-old boy with a six-month history of acne but reports no new research findings.

This review discusses the role of hormones in acne vulgaris and highlights the need for further research on their mechanisms of action; it reports no new clinical results.

This article offers strategies for managing acne effectively and safely, emphasizing treatment optimization, patient tailoring, and addressing antimicrobial resistance, but reports no new clinical results.

This study reports that obesity significantly influences cardiovascular and metabolic disturbances in women with PCOS, with overweight women experiencing more severe symptoms compared to their non-obese counterparts.

This review discusses the relationship between acne, body hair, and androgenic stimulation in adolescent girls, emphasizing treatment decisions based on disease severity rather than endocrine findings.

This review discusses the distinct clinical and psychological aspects of adult female acne and reports no new clinical results, highlighting the need for a comprehensive management approach.

This review discusses treatments for female acne, highlighting the effectiveness of low-dose oral contraceptives and noting their similar side effects to placebo; it reports no new clinical results.

This source provides a comprehensive review of acne vulgaris, highlighting its pathophysiology, epidemiology, molecular mechanisms, and treatment options, emphasizing the significance of addressing acne's psychosocial burden for adolescents and beyond.

This review discusses the chronic nature of acne and its association with various systemic diseases, but reports no new clinical findings, highlighting the need for further study on its nutritional or genetic links.

This review examines androgen status in male and female obesity and its influence on the metabolic syndrome, but reports no new clinical results.

This report shares the authors' experience using spironolactone for treating acne in a PCOS clinic, but provides no new clinical results.

This study reported that oral isotretinoin can be an effective and safe treatment for acne vulgaris when used at the appropriate dosage, offering a low-complication option.

Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.