March 2024 in “International journal of molecular sciences” This study found that human meibomian glands differ significantly from free and hair-associated sebaceous glands in morphology and lipid composition, making them highly specialized holocrine glands.
September 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study found a significant negative correlation between serum SHBG levels and androgenetic alopecia severity in women, but not in men, while no significant correlation was observed for testosterone, estradiol, dehydroepiandrosterone sulfate, and vitamin D levels with hair loss severity across genders.
July 2021 in “International Journal of Community Medicine and Public Health” This study found that testosterone levels are commonly low among men with type 2 diabetes, and most of these men exhibit symptoms of hypogonadism, with BMI being a significant risk factor.
57 citations
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December 2011 in “Lasers in Surgery and Medicine” This study suggests that selective photothermolysis of sebaceous glands using free electron laser pulses may offer a novel approach to treating acne by causing targeted thermal damage without affecting the epidermis.
13 citations
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January 1953 in “Archives of Dermatology” This research article discusses unsaturated compounds causing temporary hair loss in lab animals and reports no new results; previous studies indicated similar effects in humans.
7 citations
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March 2005 in “International Journal of Cosmetic Science” This study found that menopause alters hair lipids and reduces hair quality, with hormone replacement therapy mitigating some changes.
April 2018 in “Journal of Investigative Dermatology” This study found that sensitive scalp is characterized by increased pH levels, redness, altered sebum composition, and a disrupted microbiome, suggesting these features could inform treatment approaches.
April 2016 in “Journal of Investigative Dermatology” This study found that both topical tretinoin and oral isotretinoin altered the free fatty acid profile of sebum in acne patients, affecting bacterial growth differently for S. epidermidis and S. aureus.
September 2022 in “Medical Mycology” This study found that patients with androgenic alopecia exhibited higher levels of Malassezia colonization and altered sebum composition compared to individuals without AGA.
28 citations
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April 2014 in “Hormones” This study found that increased serum A4A levels were associated with more severe polycystic ovary syndrome phenotypes and could be a useful marker for biochemical hyperandrogenemia.
2 citations
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September 2018 in “Tissue Engineering Part A” This study found that injecting xeno-free, three-dimensional cell masses from human adipose-derived stem cells improved blood perfusion and preserved limb function in mice without causing tumors or toxicity, suggesting potential for treating severe ischemic diseases.
14 citations
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September 2020 in “Clinical, cosmetic and investigational dermatology” This study found that a hair serum containing amla extract, freeze-dried coconut water, and selenium significantly improved hair growth rate, density, and reduced hair fall among healthy volunteers over 90 days.
7 citations
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December 2016 in “Journal of The Taiwan Institute of Chemical Engineers” This study found that porcine platelet-rich plasma can be a commercially viable replacement for fetal bovine serum with similar effectiveness in promoting human hair follicle cell growth.
5 citations
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September 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that a hair serum containing amla extract, freeze-dried coconut water, selenium, sandalwood odorant, and peanut shell extract significantly improved hair growth, density, and reduced hair fall after 90 days in healthy volunteers.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this cross-sectional study at a tertiary care hospital, researchers found a significant correlation between cutaneous manifestations like hirsutism and acne and biochemical hyperandrogenism levels in women with PCOS, suggesting these skin conditions can predict elevated androgen levels.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that hirsutism and acne are strong predictors of biochemical hyperandrogenism in women with polycystic ovary syndrome.
In this case series, elderly patients with chronic pruritus reported substantial improvement after using a topical serum containing magnetized saline water, although more research is needed to confirm these results.
66 citations
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November 2001 in “European journal of endocrinology” This study suggests that decreased SHBG levels and increased FAI, free testosterone, and DHEAS concentrations are effective in diagnosing PCOS in epidemiological studies of women of reproductive age.
January 2009 in “Academic Journal of Second Military Medical University” In this study, adolescent male acne patients with normal serum testosterone showed improved outcomes with finasteride plus lifestyle intervention, significantly reducing DHT and free testosterone levels and improving SHBG levels, with minimal adverse effects.
February 2017 in “Spectrum Research Repository (Concordia University)” This study confirmed porcine PRP's commercial viability as a fetal bovine serum replacement, showing higher growth factor levels and stability, without increasing human follicle dermal papilla cell proliferation compared to FBS.
51 citations
,
May 1996 in “American journal of physiology. Regulatory, integrative and comparative physiology/American journal of physiology. Regulatory, integrative, and comparative physiology” In this study, captive gray seals exhibited increased resting metabolic rates and elevated thyroid hormone levels during the final stage of molting, with more pronounced changes in juveniles.
42 citations
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February 1985 in “Journal of the American Academy of Dermatology” This study reports that once neoplastic causes are excluded, functional hirsutism can be effectively treated with low-dose dexamethasone, oral contraceptives, and spironolactone.
36 citations
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November 2009 in “Journal of Investigative Dermatology” This study suggests that prolactin has complex, gender- and location-dependent effects on human hair follicles, promoting hair growth in female frontotemporal scalp areas while inhibiting it in male occipital regions.
20 citations
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March 2022 in “Journal of clinical medicine” This study found that late-onset hypogonadism is relatively common in male patients with long COVID, even among those under 50, and serum free testosterone measurement can help reveal this condition.
13 citations
,
December 1991 in “Annals of the New York Academy of Sciences” This study observed that human anagen hair follicles can grow in vitro when maintained serum-free, with possible implications for understanding hair follicle growth mechanisms.
13 citations
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March 2019 in “Physiological Research” This study found that among women with polycystic ovary syndrome, higher levels of the hormones estrone and free testosterone were associated with an increased cardiometabolic risk, especially in those who were overweight or obese.
11 citations
,
May 2018 in “Philosophical Transactions of the Royal Society B” This review covers recent developments in materials for in vitro and in vivo stem cell manipulation, highlighting innovative substrate properties but does not report new experimental results.
11 citations
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September 1996 in “Neuroscience letters” This study found that fetal calf serum can protect Merkel cells from death and alter their morphology in culture, while serum-free conditions led to high cell mortality.
4 citations
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January 2008 in “Journal of Shandong University” In this study, goat hair follicles cultured in serum-free medium grew faster than those in medium with serum, and growth rates increased with the addition of VEGF and EGF.
3 citations
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January 2013 This chapter discusses hypothyroidism in dogs, highlighting that most cases are due to primary thyroid gland issues and that some breeds may have a hereditary predisposition; it reports no new clinical findings.