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This review highlights the potential of several medicinal plants as treatments for seborrhea dermatitis by inhibiting Malassezia growth and reducing symptoms like itching and redness, amid challenges of drug adherence and side effects in existing therapies.

This study found that hair luster increased with higher fiber pigmentation and application of specific cosmetic oils and styling resins, while micronized ZnO and synthetic sebum dulled hair.

This review explores the current understanding of hair follicle development and regeneration, emphasizing the molecular pathways involved and the potential for bioengineering hair follicles in vitro to advance hair regeneration strategies.

In this study, inducible whole-body Acly-knockout mice revealed that ACLY is essential for skin homeostasis, as its deficiency led to increased sebum production and skin abnormalities, indicating a vital role for cytosolic acetyl-CoA synthesis in preserving skin barrier integrity and systemic lipid regulation.

In this study, HA-P5, a nanoparticle derived from peptide and polysaccharide conjugation, effectively reduced acne lesions and sebum production by inhibiting specific receptors in cells, without triggering unfavorable reactions compared to a commercial inhibitor, highlighting HA-P5's potential as a novel acne treatment.

This study found that women with PCOS exhibited higher levels of depression, tension induction, and impaired stress coping strategies compared to healthy controls, with these psychological issues correlating with hyperandrogenism but not with central obesity or insulin resistance.

This study found that Cidea is critical for regulating lipid storage and sebum secretion in sebaceous glands, with its deficiency causing hair issues and impaired skin functions in mice.

This study found that humanized mouse models expressing mutated or reduced levels of the vitamin D receptor were able to maintain normal mineral homeostasis and prevent typical symptoms of vitamin D resistance.

This study suggests the possibility of regenerating hair follicle structures in vitro using hiPSC-derived cell composites, which might reduce reliance on human tissue-derived cells for hair bioengineering.

This study found that antifungal therapy significantly reduced pustules in patients with refractory acne, indicating a potential role for Malassezia infection in such cases.

This study found that the plant Clausena anisata exhibited promising antimicrobial, antioxidant, and anti-inflammatory activities against acne-causing bacteria and inflammation, suggesting its potential as a candidate for further anti-acne treatment research.

This article discusses various holding solutions for hair transplant grafts and reports no new research findings; the authors emphasize the need for comparative studies.

This study found that training in a hypoxic chamber did not significantly impact skin features in overweight and obese women, though it did result in a notable reduction in body weight and BMI.

This study found that reducing the particle size of Tetrastigma hemsleyanum powders improved both dissolution rates and antioxidant activity, suggesting potential benefits for enhancing hepatoprotective effects.

In this study, a significant positive correlation between clinical hyperandrogenism and free androgen index was found in younger women with PCOS, but not in older women.

This Mendelian randomization study reports that lifelong increased free testosterone in males was associated with improved bone mineral density and body composition but increased risks of prostate cancer, hypertension, and several other conditions.

This review discusses the evolution of adipose tissue research in regenerative medicine, from tissue transfer to cell-free bioengineering applications, highlighting its therapeutic potential, current limitations, and future directions.

This study found that a hypoxic microenvironment enhanced the proliferation and pluripotency of adipose mesenchymal stem cells, promoting hair follicle formation and upregulating specific growth factors in Arbas Cashmere goats.

In this study, isotretinoin treatment significantly increased p53 expression in the skin of acne vulgaris patients, correlating with reduced acne severity and suggesting mechanisms for sebum suppression and side effects.

This study suggests that while PCOS phenotype does not affect oocyte quality, a combination of hyperandrogenism and chronic anovulation negatively impacts cumulative pregnancy rates in assisted reproduction.

This study investigated the effects of pathological α-synuclein on sebaceous gland cells in Parkinson's disease, finding that α-synuclein exposure altered cellular differentiation and lipid production, suggesting a potential link between α-synuclein and lipid dysregulation in the skin of PD patients.

This study suggests that bio-nanovesicles, such as exosomes and microvesicles, may enhance skin and hair follicle regeneration by modulating key signaling pathways, potentially overcoming the limitations of conventional treatments for alopecia and chronic skin diseases.

This study reported that exosomes derived from human amniotic mesenchymal stem cells (hAMSC-exo) accelerated hair growth in androgenetic alopecia mice by enhancing signals between hair follicle cells and improving cellular environments, particularly protecting against dihydrotestosterone-induced damage via Wnt/β-catenin signaling.

This study reported that in laboratory conditions, a cell-free supernatant of Bifidobacterium longum BB536 promoted human dermal papilla cell proliferation and reduced damage and apoptosis caused by dihydrotestosterone, suggesting potential use as a preventative treatment for androgenic alopecia by modulating specific signaling pathways.

In this study, researchers used a 3D in vitro organ culture system to show that rifampicin-loaded lipid nanocapsules can penetrate hair follicles more effectively than free rifampicin, highlighting the potential advantage of nanocarrier-based antibiotic treatments for follicular infections.

This review discusses the potential of P. polyphylla saponins to treat acne through antibacterial, anti-inflammatory, immunomodulatory, and antioxidant effects, noting that acne's complex pathogenesis makes this line of research promising for future studies.

In this study involving mice on a high-fat diet, piperine from black pepper was observed to reduce sebaceous gland size and fat accumulation, suggesting its potential in controlling hair oiliness by inhibiting adipogenesis in hair stem cells.

In this study, researchers developed a novel platform for discovering potential hair loss inhibitors by investigating the testosterone/dihydrotestosterone biosynthetic pathway and its regulation through biochemical mechanisms involving 17β-HSD and 3β-HSD, combined with medicinal plant extracts.

This review highlights the importance of standardizing pre-analytical procedures for collecting and extracting samples from uncommon biological specimens like breast milk and sweat in clinical metabolomics, to enhance diagnostic and biomarker discovery efforts while minimizing contamination and bias.

This review discusses the causes and recommended clinical investigations for postmenopausal hyperandrogenism, highlighting the role of androgen excess in symptoms like hirsutism and its association with metabolic disorders.