November 2025 in “Khalij-Libya Journal of Dental and Medical Research” In this study, Libyan patients with diffuse hair loss were found to have significantly lower levels of zinc, ferritin, and vitamin D compared to those without hair loss, suggesting a possible link between these micronutrient deficiencies and hair loss.
1 citations
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January 2025 in “Pediatria i Medycyna Rodzinna” This case report of a 16-month-old girl with acrodermatitis enteropathica, who showed atypical symptoms and normal zinc serum levels, highlights how genetic testing and zinc supplementation led to marked improvement in her condition, underscoring the importance of accurate diagnosis in metabolic disorders.
54 citations
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June 2001 in “The Indian Journal of Pediatrics” This study found that newborns with neural tube defects and their mothers had significantly lower hair zinc levels compared to controls.
5 citations
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May 2020 in “Diagnostics” This study involving male patients with androgenic alopecia found that a higher baseline zinc plasma level, specifically above 10 µmol/L, may predict the success of treatment with 5% topical minoxidil, correlating with increased hair density and diameter in the parietal area.
2 citations
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January 2011 This study found that zinc levels were significantly decreased in both alopecia areata and vitiligo patients compared to controls, suggesting zinc may play an important role in the etiopathogenesis of these conditions.
1 citations
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November 2011 in “Dermatologica Sinica” This study found a significant decline in serum zinc levels among women of African descent using hair relaxers and experiencing alopecia, with age at first exposure potentially influencing alopecia development.
October 2023 in “Acta dermato-venereologica (Print)” This study found that patients with severe alopecia areata had significantly lower serum zinc levels compared to healthy controls, and a negative correlation between zinc levels and disease severity was observed, suggesting that zinc assessment and supplementation trials may be warranted in this population.
This study found a correlation between zinc levels in hair and serum, and alkaline phosphatase activity in acne phlegmonosa and alopecia areata patients.
2 citations
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December 2015 in “Journal of dermatology research and therapy” This study compared serum zinc, vitamin B12, folic acid levels, iron metabolism, and thyroid function between chronic telogen effluvium patients and healthy controls, but it reports no specific clinical results.
1 citations
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January 2023 in “International journal of urology” In this study, researchers observed that lower serum zinc concentrations were associated with decreased serum testosterone levels, but no link was found with sexual function questionnaire scores.
December 2021 in “Dermatology research” This study found that individuals with premature graying of hair had significantly lower serum levels of vitamin B12, ferritin, and calcium compared to those without premature graying.
July 2018 in “Journal of College of Medical Sciences-nepal” This study found a significant association between lower serum ferritin levels and chronic diffuse hair loss in women of reproductive age, particularly in cases of alopecia areata and androgenetic alopecia.
5 citations
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December 2024 in “Journal of Cosmetic Dermatology” Vitamin D and zinc may help treat alopecia areata.
23 citations
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February 2017 in “Journal of dermatology” This meta-analysis suggests that patients with alopecia areata have lower serum levels of zinc and selenium compared to healthy controls, which may be important risk factors for the condition.
January 2024 in “Biological trace element research” In this study, isotretinoin treatment for acne vulgaris was associated with changes in plasma phosphorus, potassium, magnesium, and zinc levels, potentially affecting kidney function and contributing to side effects like fatigue and dry skin.
April 2021 in “MEDICINUS” This case report describes a 5-year-old boy with acquired acrodermatitis enteropathica and normal serum zinc levels, improving clinically after zinc supplementation.
73 citations
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May 1976 in “JAMA” This case report associates severe zinc deficiency with long-term total parenteral nutrition, suggesting the need for trace element supplementation in such nutritional management.
39 citations
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July 2007 in “SKINmed Dermatology for the Clinician” In this case study, a 4-year-old girl's hair loss stopped after six months of zinc supplementation and dietary changes, suggesting a possible link to low zinc levels.
34 citations
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August 2005 in “Veterinary Dermatology” This descriptive study reports that zinc deficiency in two dairy goats likely resulted from hereditary malabsorption, requiring life-long zinc supplementation to prevent skin lesions.
27 citations
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March 2012 in “Dermatologic Therapy” In this study, all five patients with zinc deficiency-related hair loss experienced improvement or recovery of their condition after receiving oral zinc treatment.
12 citations
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July 1979 in “International Journal of Dermatology” This article reviews the clinical manifestations and contributing factors of acute zinc depletion syndrome, reporting no new results but discussing prevention and treatment strategies.
11 citations
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January 2011 in “Turkish Journal of Medical Sciences” This study found that iron deficiency anemia is a key factor in the development of telogen effluvium, and higher 25-hydroxyvitamin D3 levels in TE patients may be linked to increased UV exposure.
3 citations
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November 2022 in “Frontiers in oncology” This study found that while serum zinc concentrations were not associated with developing gynecologic cancers, zinc deficiency was linked to a higher recurrence rate.
2 citations
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December 2019 in “The Iraqi Journal of Veterinary Medicine” This study found that experimentally induced zinc deficiency in Iraqi goats significantly affected their overall health, including changes in hematological parameters and clinical signs, suggesting potential economic losses.
February 2023 in “Global journal of health sciences and research” This study found no association between serum zinc levels and alopecia areata severity in patients.
June 2022 in “International Journal of Health Sciences (IJHS) (En línea)” This study found that pregnant women in Al Muthanna Province, Iraq, frequently have low serum zinc and ferritin levels, especially those experiencing hair loss, posing a significant public health concern.
January 2022 in “United Research Forum eBooks” In this study, picky eating among children in southern Jordan was associated with lower weight for age, hemoglobin levels, and vitamin D levels, rather than directly with zinc deficiency.
February 2021 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study found that women with telogen effluvium had significantly lower serum copper and zinc levels compared to controls, suggesting these deficiencies may be associated with the condition.
January 2006 in “Trace Elements Science” This study observed that Wistar rats on a zinc-deficient diet had a higher incidence of stomach cancer when exposed to MNNG, suggesting zinc deficiency may increase cancer risk.
January 2026 in “University of Science and Technology Institutional Repository (University of Science and Technology, Sana’a, Yemen)” This study found that adult males in Taiz, Yemen with dermatological disorders had significantly lower serum zinc and hemoglobin levels compared to healthy controls, highlighting the importance of assessing micronutrient status in skin disease management.