56 citations,
July 2008 in “European journal of endocrinology” Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.
45 citations,
February 2019 in “Journal of Affective Disorders” Melatonin improved mental health and metabolism in women with PCOS.
40 citations,
April 2008 in “European journal of endocrinology” Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.
31 citations,
September 2020 in “Clinical endocrinology” Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
25 citations,
January 2013 in “International Journal of Trichology” Premature balding in some men may be linked to altered hormones, but it's not the male equivalent to polycystic ovary syndrome or metabolic syndrome.
21 citations,
January 2021 in “Therapeutic Advances in Endocrinology and Metabolism” Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.
14 citations,
May 2019 in “Human gene therapy” MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.
10 citations,
January 2000 in “PubMed” Both finasteride and GnRH agonist treatments reduced hair growth in women with idiopathic hirsutism, but GnRH agonist was more effective.
5 citations,
October 2016 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Women with PCOS may have a higher risk of respiratory and ear infections due to slower nasal mucociliary clearance.
December 2019 in “Mehmet Akif Ersoy Üniversitesi Sağlık Bilimleri Enstitüsü dergisi” One cat with low thyroid hormone had growth issues, and another with high thyroid hormone had skin problems; both got better with treatment.
October 2018 in “International journal of reproduction, contraception, obstetrics and gynecology” Higher testosterone levels in Nigerian women with PCOS are linked to glucose disorders like diabetes.
January 2014 in “Journal of the Egyptian Women's Dermatologic Society (Print)” Women with acne after adolescence are more likely to have PCOS and should be checked for it.
March 2009 in “The Journal of Urology” Low dose finasteride causes only minor changes in PSA levels in men over 50 with BPH.
77 citations,
November 2007 in “International Journal of Andrology” Testosterone with or without finasteride doesn't improve thinking skills in older men with low testosterone.
10 citations,
February 2008 in “International Journal of Andrology” A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.
1 citations,
October 2020 in “Journal of Cosmetic Dermatology” Possible link between hair loss and metabolic syndrome, with RANTES as a potential clue.
506 citations,
March 2005 in “The Journal of Clinical Endocrinology and Metabolism” Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.
72 citations,
April 2008 in “The Journal of urology/The journal of urology” Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.
10 citations,
August 2014 in “Skin research and technology” Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.
5 citations,
August 2018 in “Sexual Medicine Reviews” 5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
4 citations,
January 2015 in “Journal of microbial & biochemical technology” Biotin helps regulate proteins in the blood, which may explain its role in hair growth.
417 citations,
February 2004 in “The Journal of Clinical Endocrinology and Metabolism” Testosterone therapy increases bone density in older men with low testosterone levels.
3 citations,
April 2019 in “Hormone and Metabolic Research” Women with PCOS have lower adiponectin hormone levels and are more likely to have insulin resistance.
25 citations,
September 2015 in “Clinical Endocrinology” Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.
June 2021 in “The American Journal of the Medical Sciences” Androgenetic alopecia is linked to a higher risk of coronary heart disease due to certain genetic factors and high homocysteine levels.
2 citations,
November 2019 in “Case reports in women's health” Ovarian vein sampling helped diagnose rare ovarian tumors causing high testosterone, and surgery to remove the tumors lowered the testosterone levels.
February 2024 in “Heliyon” People with androgenetic alopecia have different lipid levels in their blood, which vary between men and women, and may be linked to a higher risk of metabolic syndrome.
September 2023 in “Diagnostics” Low vitamin D levels may affect ovulation and progesterone in infertile women.
January 2023 in “International journal of clinical medicine” Women with PCOS and hair loss have lower levels of the protein gelsolin in their blood.
5 citations,
March 2022 in “Frontiers in Endocrinology” A model using hormone levels, cycle length, and BMI can help identify PCOS in Chinese women but isn't for screening teens.