46 citations,
September 2015 in “Fertility and Sterility” Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.
42 citations,
September 2015 in “Gene” FGF5s can block the effects of FGF5, which may help control hair growth in cashmere goats.
40 citations,
December 2016 in “Journal of Dermatological Treatment” JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.
40 citations,
January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.
32 citations,
August 2020 in “Cytokine” Type I interferons play a key role in the development of various skin diseases.
32 citations,
January 2012 in “International Journal of Dermatology” Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.
28 citations,
July 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
28 citations,
January 2003 in “Skin pharmacology and physiology” Melatonin affects skin cell growth differently based on how much and how long it's used.
27 citations,
October 2015 in “Neuropharmacology” Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
27 citations,
November 2006 in “Laboratory Investigation” SCF and ET-1 together significantly increase skin pigmentation and melanin production.
26 citations,
May 2012 in “Cellular and Molecular Life Sciences” NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
26 citations,
September 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
26 citations,
January 2000 in “Hormone research in paediatrics” Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.
25 citations,
November 2018 in “Molecular Biology of the Cell” Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
25 citations,
June 2004 in “Journal of Investigative Dermatology” Macrophage-stimulating protein helps hair grow and can start hair growth phase in mice and human hair samples.
24 citations,
January 2006 in “Journal of Cellular Biochemistry” Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
22 citations,
August 1999 in “Experimental Dermatology” Certain drugs can cause early hair growth in mice by affecting the nerves.
21 citations,
March 2019 in “Critical Reviews in Clinical Laboratory Sciences” The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
21 citations,
October 1980 in “Gastroenterology” The report described a unique case of Cronkhite-Canada syndrome with unusual polyps and an association with multiple myeloma.
20 citations,
September 2006 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” New drugs are improving treatment for hormone-related diseases in small pets.
19 citations,
November 2012 in “British Journal of Dermatology” Dopamine stops hair growth and pigment production in human scalp hair follicles.
19 citations,
January 2007 in “Biological & pharmaceutical bulletin” Glycine reduces skin pigmentation by lowering melanin production.
18 citations,
March 2015 in “Journal of Endocrinological Investigation” The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.
18 citations,
January 2004 in “Dermatologic Clinics” Skin problems in older people can indicate hormonal diseases, nutritional deficiencies, or conditions like diabetes, menopause, and HIV.
15 citations,
February 2019 in “Journal of clinical medicine” Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.
12 citations,
February 2012 in “New England journal of medicine/The New England journal of medicine” A 72-year-old man had severe fatigue, weight loss, and frequent loose stools.
11 citations,
January 2020 in “BMC pediatrics” New mutations in the SLC39A4 gene found in twins help understand the genetic cause of acrodermatitis enteropathica.
11 citations,
October 2019 in “Cancers” Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.
11 citations,
August 2018 in “Nutrition Research” Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.
10 citations,
January 2019 in “in Vivo” Finasteride boosts stem cell signals for hair growth.