research 5-Alpha-Reductase Inhibitors and Combination Therapy
Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.
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research Sexual Desire in a Sample of Married Egyptian Women with Polycystic Ovarian Syndrome
Married Egyptian women with PCOS have lower sexual desire compared to those without PCOS.
research The Mechanisms and Management of Age-Related Oxidative Stress in Male Hypogonadism Associated with Non-Communicable Chronic Disease
Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.
research To Study Hypoactive Sexual Desire Disorder in a Fragile X Carrier Female Successfully Treated with Local Testosterone Application
Local testosterone treatment improved sexual desire in a female with fragile X syndrome.
research A Systematic Review of Antiandrogens and Feminization in Transgender Women
Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
research Finasteride, Not Tamsulosin, Increases Severity of Erectile Dysfunction and Decreases Testosterone Levels in Men With Benign Prostatic Hyperplasia
Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.
research Comparison of Finasteride (Proscar) and Serenoa Repens (Permixon) in the Inhibition of 5-Alpha Reductase in Healthy Male Volunteers
Finasteride works better than Permixon in reducing dihydrotestosterone levels.
research Association of Early-Onset Androgenetic Alopecia and Metabolic Syndrome
Early-onset hair loss in young males is linked to a higher risk of metabolic syndrome.
research Clinical Evaluation of Women Presenting with Low Libido and Determination of Whether Androgen Therapy Might Be Appropriate
Androgen therapy might help some women with low libido, but it has risks and should be used carefully.
research Ovarian Leydig Cell Tumor in a Post-Menopausal Patient with Severe Hyperandrogenism
An 81-year-old woman's severe male hormone symptoms were caused by an ovarian tumor, which was treated with surgery.
research Effect of Castration and Finasteride on Urinary Oxalate Excretion in Male Rats
Castration and finasteride lower urinary oxalate in male rats, potentially treating urolithiasis.
research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Lowering testosterone speeds up wound healing in male mice.
research Androgen Receptor in Rat Liver: Characterization and Separation from a Male-Specific Estrogen-Binding Protein
Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.
research Polycystic Ovary Syndrome: Comprehensive Overview and Diagnostic Criteria
PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.
research Comparison of Clinical and Metabolic Effects of Metformin and Pioglitazone in Polycystic Ovary Syndrome
Both metformin and pioglitazone improve PCOS symptoms, but pioglitazone is a good alternative for those who can't take metformin.
research Androgens in SARS-CoV-2 Coronavirus Infections
Men, particularly those with hair loss, are more likely to get the virus, and those with prostate cancer may have milder symptoms. Testosterone's role in the disease is unclear, and the virus doesn't seem to harm male fertility. Women with PCOS might be at higher risk. More research is needed.
research Genetics and Epigenetics of Polycystic Ovary Syndrome
Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.
research Dihydrotestosterone Induces Proliferation, Migration, and Invasion of Human Glioblastoma Cell Lines
Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.
research The Mechanisms of Anabolic Steroids, Selective Androgen Receptor Modulators, and Myostatin Inhibitors
Anabolic steroids boost muscle growth, SARMs increase muscle mass and bone density without side effects, and myostatin inhibitors block a protein that stops muscle growth, but each has potential risks.
research Controversies Regarding Transdermal Androgen Therapy in Postmenopausal Women
Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.
research Testosterone in COVID-19: An Adversary Bane or Comrade Boon
Testosterone's effects on COVID-19 are unclear and need more research.
research Dihydrotestosterone Induces Arterial Stiffening in Female Mice
Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.
research The Effect of Finasteride on the Male Rat Brain
Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.
research Polycystic Ovary Syndrome Patients with High BMI Tend to Have Functional Disorders of Androgen Excess: A Prospective Study
Overweight women with PCOS are more likely to have excess male hormones.
research Comorbid Laboratory Abnormalities in Female Pattern Hair Loss Patients
Many women with hair loss also have zinc deficiency, iron depletion, or thyroid issues.
research Severe Hyperandrogenemia and Insulin Resistance in a 12-Year-Old Girl
A 12-year-old girl with very high testosterone and insulin resistance improved with birth control pills, suggesting PCOS can cause high testosterone without tumors.
research Genetic Basis of Polycystic Ovary Syndrome
The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.
research Testosterone: The Male Sex Hormone
More research is needed to understand how testosterone is maintained in adult males.
research Long-Term Dutasteride Therapy in Men with Benign Prostatic Hyperplasia Alters Glucose and Lipid Profiles and Increases Severity of Erectile Dysfunction
Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
research Androgens and Ovarian Function: Translation from Basic Discovery Research to Clinical Impact
Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.