8 citations
,
January 2019 in “Annals of Dermatology” Among cultured sebocytes, this study found that bilobetin significantly inhibited lipid production induced by IGF-1, suggesting potential for use in acne treatment.
7 citations
,
August 2017 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” This study found that lower serum vaspin levels (below 3.74ng/mL) may predict successful ovulation induction with clomiphene citrate in anovulatory women with PCOS, indicating potential resistance when levels are higher.
5 citations
,
August 2018 in “Sexual Medicine Reviews” In this review and meta-analysis, the authors concluded that 5α-reductase inhibitor therapy is not consistently associated with significant increases in serum testosterone levels in men.
4 citations
,
September 2024 in “Frontiers in Endocrinology” This study found that serum steroid profiling, particularly 11-deoxycortisol, can effectively differentiate between ACC and ACA, while considering sex differences and functional status for other steroids is important.
January 2026 in “International Journal of Pharmaceutical Quality Assurance” In this study, researchers observed that patients with Alopecia Areata had significantly lower serum zinc and higher copper levels compared to healthy controls, indicating a disrupted zinc-copper balance that may contribute to the disease's pathogenesis.
August 2023 in “International journal of basic and clinical pharmacology” This review article describes the ingredients and evaluation tests for formulating a hair serum aimed at improving hair growth and preventing hair loss, highlighting the roles of Citrus sinensis, Nigella sativa, flax seed, and coconut oil in addressing hair and scalp health.
June 2023 in “Journal of chemical metrology” This study used LC-HRMS to detect undeclared pharmaceutical ingredients like minoxidil and finasteride in hair serums, finding risk to public health due to their toxicological properties and advocating for manufacturer transparency.
July 2022 in “International Journal of Health Sciences (IJHS) (En línea)” In this study, researchers found that serum dihydrotestosterone levels were significantly lower in individuals with Type 2 Diabetes compared to healthy controls, with 90% of diabetics displaying subnormal levels.
This study examined serum PSA levels in women with androgenetic alopecia to evaluate their potential as a marker for androgen effects on target organs.
506 citations
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March 2005 in “The Journal of Clinical Endocrinology and Metabolism” This study found that testosterone therapy improved physical performance and strength in older men with low testosterone over 36 months, whether administered alone or with finasteride.
78 citations
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August 2012 in “Human molecular genetics online/Human molecular genetics” This study found that three genetic loci, including the newly identified JMJD1C, are associated with circulating testosterone and dihydrotestosterone levels, explaining a small portion of their variance in European men.
72 citations
,
April 2008 in “The Journal of urology/The journal of urology” This study found that 1-year use of 5alpha-reductase inhibitors, dutasteride or finasteride, significantly lowered dihydrotestosterone levels without adversely affecting bone density, lipids, or hemoglobin in normal men.
30 citations
,
August 1992 in “The Journal of Clinical Endocrinology and Metabolism” This study found that lowering serum DHT levels with 5 mg finasteride daily did not significantly alter serum gonadotropin levels in healthy young men after 28 days.
16 citations
,
January 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that serum PSA levels are higher in hirsute women and can be significantly reduced by antiandrogen treatment, suggesting PSA as a marker of androgen action in females.
11 citations
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May 2010 in “Journal of Medicinal Chemistry” This study introduced a novel nonsteroidal androgen receptor antagonist that effectively controls sebum production in the golden Syrian hamster ear model through targeted follicular delivery.
5 citations
,
April 2021 in “Journal of Endocrinological Investigation” This study concluded that among men with normal testosterone levels, a small increase in serum dihydrotestosterone may reduce symptoms of hypogonadism, suggesting its potential diagnostic use after ruling out hypogonadism.
1 citations
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September 2016 in “Springer eBooks” This article reports no new data; it describes the role of sebum in influencing the skin microbiome and epithelial tissues and discusses its altered composition during transit through the sebaceous duct.
February 2022 in “Global academic journal of medical sciences” This study observed lower vitamin D levels in alopecia areata patients compared to healthy controls and suggested a possible causal role of vitamin D deficiency in the condition.
December 2025 in “Frontiers in Endocrinology” This study found that elevated CgA levels in PCOS are associated with obesity, insulin resistance, and low-grade inflammation, suggesting CgA may be a novel biomarker for metabolic risk stratification in PCOS.
18 citations
,
July 2009 in “Drug Metabolism and Disposition” This study identified previously unknown phase I and phase II metabolites of finasteride in human bile and urine using a specialized bile collection technique and advanced mass spectrometry analysis.
11 citations
,
July 2021 in “Nanomaterials” This study found that α-13′-carboxychromanol significantly accelerated wound healing and improved tissue quality in a mouse model, especially when delivered with bacterial nanocellulose under diabetic conditions.
2 citations
,
December 2013 in “Xenobiotica” This study found that the metabolic profile of finasteride in pigs closely matches that of humans, supporting the use of pigs for studying human drug metabolism.
1 citations
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June 2024 in “International Journal of Drug Delivery Technology” This review suggests that herbal hair serums, which are claimed to nourish the scalp and promote hair growth, may effectively treat alopecia without adverse effects, offering a natural alternative to allopathic medications that often have side effects.
August 2025 in “International Journal of Advanced Research in Science Communication and Technology” This study found that hybrid hair serums combining natural and synthetic ingredients may significantly enhance hair growth, density, and texture, highlighting their potential benefits for improving hair health and appearance.
417 citations
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February 2004 in “The Journal of Clinical Endocrinology and Metabolism” This study found that testosterone therapy increased bone mineral density in older men with low testosterone, and combining it with finasteride may reduce prostate enlargement associated with testosterone treatment.
This article provides tables summarizing various medical conditions and symptoms related to COVID-19, sepsis, and cardiovascular issues, but it does not report new research findings.
May 2025 in “REVISTA DA ASSOCIAÇÂO DE FARMÁCIAS VIVAS” This study introduced an innovative antioxidant serum for skin care, using a lipid active from Rana catesbeiana Shaw, and validated its rejuvenating potential through physical-chemical and microbiological tests that ensured its antioxidant effectiveness, microbiological safety, and formulation stability.
112 citations
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May 2019 in “Pharmacological Research” This review discusses the isolation, structure, and bioactivity of lignans and neolignans from 2016 to mid-2018, reporting no new clinical results but highlighting their potential protective properties against diseases such as cancer and neurodegeneration.
23 citations
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June 2015 in “Clinica Chimica Acta” In this study, researchers identified two potential urinary biomarkers, testosterone–glucuronide and 11α-hydroxyprogesterone, along with four candidate biomarkers, to help understand and diagnose polycystic ovary syndrome.
21 citations
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January 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” In this study, researchers demonstrated that in a mouse model, the stimulation of mammary tumor growth due to progesterone is primarily caused by its metabolite, 5αP, not progesterone itself.