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The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Fat cells help recruit healing cells and build skin structure during wound healing.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Testosterone's muscle-building effects do not require its conversion to DHT.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Liposomes could improve how skin care products work but are costly and not very stable.

Hair loss linked to higher heart disease risk in both men and women.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

DHT may increase the risk of heart disease and death in elderly men.

Medications have become the main treatment for enlarged prostate symptoms, replacing surgery and watchful waiting.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Triparanol therapy can cause hair loss and skin dryness without inflammation or damage to hair follicles or skin structures.

Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.