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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

PCOS is common among Chinese women of reproductive age and linked to serious metabolic and reproductive issues, especially in obese women.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Apoptosis is essential for human skin development and forming a functional epidermis.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Human skin can make serotonin and melatonin.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Patients need long-term care after bariatric surgery to manage potential nutritional and metabolic issues.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Androgens can both increase and decrease hair growth in different parts of the body.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.