March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study aims to create and evaluate a novel trio pack of polyherbal hair care products, that includes a shampoo, conditioner, and serum, leveraging diverse botanical extracts known for promoting hair growth and scalp health, while reducing side effects typical of chemical-based cosmetics.
4 citations
,
March 2022 in “Journal of Cosmetic Dermatology” This study found that formulations containing saccharide isomerate significantly improved scalp flaking, sebum secretion, and transepidermal water loss compared to placebo in an adult Chinese population with dandruff.
7 citations
,
May 2012 in “International Journal of Andrology” This study found that an oral testosterone formulation normalized serum testosterone levels and significantly reduced SHBG in men with experimentally induced hypogonadism after nine days of treatment, suggesting potential efficacy for testosterone deficiency.
November 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study found that both oral and topical formulations of VISPOTM, a saw palmetto oil, significantly reduced hair fall and increased hair density in subjects with androgenetic alopecia, with no serious adverse effects observed.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights recent findings on the polyherbal formulations for dandruff management, indicating these offer promising, eco-friendly alternatives with multiple health benefits compared to conventional anti-dandruff shampoos that may cause adverse effects with prolonged use.
42 citations
,
July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” This study suggests that heparan sulfate is crucial for regulating hair follicle formation, cycling, and gland morphogenesis, with its ablation leading to continuous hair growth and increased gland activity in mice.
4 citations
,
January 2015 in “Endocrinology & metabolic syndrome” This article discusses the role of testosterone in the formation of male characteristics, muscle and bone development, and its impact on skin and hair, but provides no new clinical results.
1 citations
,
May 2022 in “Pharmaceutics” This study found that a developed nanostructured lipid carrier formulation of tea seed oil can effectively stimulate hair growth and reduce the oily feeling associated with direct application.
November 2025 in “Frontiers in Pharmacology” In this study, XZYFD, a Traditional Chinese Medicine formulation, was found to improve androgenetic alopecia in a testosterone-induced mouse model by promoting hair regrowth, restoring follicular morphology, and modulating androgen metabolism, MAPK signaling, and lipid metabolism pathways, suggesting potential benefits for patients with metabolic dysfunction.
78 citations
,
September 2006 in “International Journal of Cosmetic Science” This paper discusses the role of Malassezia yeast and inflammation in dandruff and highlights the potential of anti-inflammatory antidandruff formulations to improve scalp conditions and hair cycle disturbances; it presents no new experimental results.
March 2026 in “Skin Appendage Disorders” This narrative review highlights the distinct needs of pediatric hair care, emphasizing gentler formulations due to differences in children's hair physiology, structure, and barrier function, and calls for targeted regulations and research due to limited safety evidence.
34 citations
,
October 2014 in “European journal of pharmaceutics and biopharmaceutics” This study found that adapalene-loaded solid lipid microparticles may enhance targeted drug delivery into sebum due to their similarity to sebum components, although both this formulation and a standard cream showed equivalent follicular penetration.
June 2022 in “Farmacevtičnij časopis” This study developed a technology for a combined gel named "Biosedum Plus" intended for treating and preventing radiation skin damage, detailing its formulation and critical processing parameters.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this review, the authors highlight the growing use of herbal cosmetics in the personal care industry due to their health benefits, emphasizing the importance of quality control and safety in these increasingly popular natural formulations.
262 citations
,
May 2020 in “Advanced Functional Materials” This study demonstrated that a newly developed polypeptide-protein hydrogel with vascularization and antibacterial properties promoted tissue regeneration and hair follicle formation in infected wound healing.
5 citations
,
April 2023 in “BMC Microbiology” This study found that using a shampoo containing heat-killed probiotics, GMNL-653, led to decreased dandruff and sebum production and increased hair growth in human participants, with observed microbiota shifts including changes in M. globosa and M. restricta abundance.
November 2023 in “ACS Omega” This study reported that a novel cationic liposome formulation for delivering encapsulated Cas9 protein and sgRNA successfully decreased SRD5α2 mRNA expression by 29.7% in vitro, suggesting a potential alternative treatment option for conditions like prostate cancer and benign prostatic hyperplasia without current drug side effects.
18 citations
,
November 1998 in “Comparative biochemistry and physiology. Part A, Molecular & integrative physiology” This study found that serum prolactin and dehydroepiandrosterone levels did not determine the onset of mink hair growth cycles, though their metabolites may influence other aspects of hair growth.
6 citations
,
May 2016 in “Urolithiasis” This study found that the risk of urinary stone disease increased significantly in patients with severe androgenetic alopecia, and that testosterone deficiency was more frequent among these patients.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a natural hair serum using rice and guava leaf extracts, evaluating its composition and properties for improving hair quality, reducing hair fall, and nourishing the scalp, though specific results are not detailed in the abstract.
June 2026 in “International Journal of Innovative Science and Research Technology (IJISRT)” This study aimed to create and evaluate a herbal hair serum containing curry leaf and hibiscus extracts, formulated to promote hair growth and reduce hair loss using castor and almond oils as the base.
May 2026 in “Journal of Drugs in Dermatology” This study reports that a dual cosmetic serum system by KilgourMD significantly improved hair loss in predominantly menopausal women over a 4-month period, as evidenced by objective and clinical assessments.
May 2024 in “International Journal for Research in Applied Science and Engineering Technology” This study reported that an herbal hair serum developed for general hair treatment met all assessment criteria, suggesting potential as a safer alternative to synthetic hair products.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study highlights the multifunctional benefits of natural hair oils, like coconut and argan, for nourishing and protecting hair, while addressing safety and sustainability as key factors in their evolving use and formulation within cosmetic science.
11 citations
,
September 1997 in “Archives of Dermatology” Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.
June 2026 in “International Journal of Research in Dermatology” This study found that Indulekha Bringha scalp serum significantly reduced hair shedding and improved hair density more effectively than 3% Redensyl serum in healthy Indian adults experiencing hair loss.
October 2025 in “Research Journal of Topical and Cosmetic Sciences” This study evaluated a herbal scalp serum containing Phyllanthus Emblica, hibiscus, Vitamin E, aloe Vera, and citrus oil, finding it stable and possessing good antibacterial activity.
October 2025 in “Research Journal of Science and Technology” This research abstract describes an herbal hair serum formulated with aloe vera, rose water, coconut oil, and essential vitamins, purported to improve hair health, texture, and manageability naturally without chemicals, although specific results are not reported.
In this study, Biosea® Revive serum, containing biotinoyl tripeptide-1 and Phyllanthus emblica extract, was found to improve hair density and quality in a 90-day clinical trial without adverse effects, offering a potential natural solution for hair growth.
January 2025 in “Journal of Applied Pharmaceutical Science” This study examined the effectiveness of peppermint essential oil formulated into a nanoliposome gel for enhancing hair growth, finding that this preparation increased hair growth in male Sprague Dawley rats without causing irritation, suggesting it may improve delivery of these active ingredients.