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Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Recognizing and managing central sensitization and stress is crucial for treating chronic pain.

PCOS may increase the risk of mental health issues like depression and anxiety.

Women with early-onset baldness should be checked for early bone loss, but bone density doesn't change with baldness severity.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Frontal Fibrosing Alopecia might be an autoimmune disease.

Women with acne have lower levels of a specific hormone marker than women without acne.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Studying acne-related syndromes helps us understand acne causes and can lead to new treatments.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Many women in southern China have polycystic ovary syndrome, with some symptoms differing from Western women.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.

Laser hair removal is effective for dark hair but needs improvement for nonpigmented or fine hairs.

Changes in prolactin and DHEA levels are not required for the start of mink hair growth cycles.

No strong link between testosterone or DHEAS levels and acne or hair loss in females.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

Women with excessive male-pattern hair growth should get a full hormone check-up to find and treat any underlying issues, considering both medical and emotional aspects.

The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.

Hirsutism requires identifying the cause to choose the right treatment, which may include medications like oral contraceptives or dexamethasone.

Skin symptoms like fragile skin and easy bruising can indicate Cushing's syndrome, which requires early diagnosis and treatment to prevent serious health issues.

The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.

No significant hormone differences found in postmenopausal women with androgenetic alopecia.