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The document says that early treatment of Acne Vulgaris is important to prevent scarring and that adult onset acne is common in women, often due to hormonal imbalances.

Normal-range ALT levels can indicate metabolic and hormonal imbalances in young women.

Skin changes in women with PCOS are mainly due to hormonal imbalances.

Young women with PCOS and no other heart risk factors have normal heart function.

Estrogens and progesterone are key in regulating melasma pigmentation.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Hair loss affects quality of life, self-esteem, and confidence, but younger patients cope better.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Low birthweight and rapid weight gain after birth may increase the risk of developing polycystic ovary syndrome.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Anti-androgens are safe and effective for treating moderate to severe adult female acne.

Certain gene variations may protect against skin issues and oxidative stress in women with PCOS.

The skin produces and processes hormones, affecting both local and overall body functions.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

High levels of cortisol in hair show long-term stress which can lower fertility in animals.

A woman's high testosterone levels and related symptoms improved after ovary removal surgery.

Women with acne and irregular periods had higher active testosterone levels, which could suggest the usefulness of antiandrogen treatment.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Women with persistent acne and high levels of antimullerian hormone are more likely to have polycystic ovarian syndrome.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Gene mutations can cause problems in male genital development.

Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.

The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.

Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.

New genes and pathways are important for testosterone production and male sexual development.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.