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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Finasteride reduces prostate size and PSA levels in young patients.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Finasteride exposure harms tadpole reproduction and hormone balance.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

Giving melatonin to sheep before the non-breeding season can improve their chances of reproducing in northwest Mexico.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

The document explains how sperm cells are produced, the role of testosterone in this process, and how toxins can reduce sperm count and fertility.

A postmenopausal woman's increased male hormone levels were successfully treated with surgery.

A dog's hair loss was caused by a hormone-secreting testicular tumor.

Genetic testing for cancer risk can lead to early and life-saving treatments in people without symptoms.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

Chesapeake Bay retrievers' hair loss is likely a breed-specific, hereditary condition linked to abnormal steroid levels and distinct skin changes.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.

Bald men may have a lower risk of testicular cancer.

Different types of hair loss in dogs and cats have various causes and treatments, with outcomes ranging from good to uncertain.

Low-dose finasteride may cause fertility issues, but stopping it can improve sperm quality and lead to pregnancy.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

The document is a detailed guide on skin conditions and treatments for dermatologists.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.