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Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Hormonal imbalances, often indicating conditions like PCOS, are common in women with hard-to-treat acne, and a treatment approach addressing these imbalances may be needed.

Finasteride can cause sexual problems and depression in young men.

Dermatologists should screen for and manage psychological issues in patients with skin conditions to improve their quality of life.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

The 2018 update to the ED care model added a new severity score and stressed a detailed evaluation of both physical and psychological aspects.

Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.

Finasteride may cause mental and sexual side effects, with hand preference and sexual orientation possibly affecting severity.

PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.

Chronic kidney disease can cause skin problems that affect patient quality of life, and treating these conditions can improve outcomes.

Adrenal gland disease is common in ferrets and causes hair loss and other symptoms.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Stress hormones like cortisol may trigger psoriasis flare-ups.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Estazolam reduces anxiety-like behavior in PTSD by increasing allopregnanolone levels.

Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.

Older adults still engage in sexual activities but face challenges like health issues and lack of professional support, highlighting the need for better healthcare provider education and research on sexual fulfillment in old age.

Platelet-rich plasma therapy could be an effective treatment for melasma with minimal side effects.

Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.

Substance abuse can cause various skin problems, including marks from injections, sores, premature aging, and increased cancer risk.

Valproate is a mood stabilizer for bipolar disorder but has side effects and risks, especially during pregnancy.

Obstetrician/gynecologists can diagnose and manage female hair loss with careful history taking and examination.