February 2026 in “Frontiers in Medicine” This study reported that trichoscopy can identify specific hair shaft abnormalities linked to increased serological activity, highlighting its use as a valuable non-invasive diagnostic tool in pediatric dermatology for neonates with ECS.
April 2023 in “Research Square (Research Square)” This study found that lower GPX4 mRNA levels in polymorphonuclear neutrophils of systemic lupus erythematosus patients were negatively associated with disease activity and serological markers, suggesting a diagnostic value for GPX4 mRNA.
January 2026 in “Frontiers in Medicine” This study suggests that coexisting LSS and TSPEAR variants might contribute to a complex phenotype of congenital hypotrichosis and ectodermal abnormalities in a child, and highlights the need for cautious interpretation of genotype-phenotype links and the potential value of broader genetic testing.
May 2025 in “JEADV Clinical Practice” This study found that laboratory testing practices for alopecia areata vary among international hair experts, with the majority routinely conducting thyroid function and complete blood count tests, yet exhibiting diverse approaches toward testing for other conditions or before prescribing systemic therapy.
2 citations
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April 2024 in “AIDS Research and Therapy” This case highlights the importance of considering syphilis testing for patients with unusual symptoms like hair loss and hypopigmentation, emphasizing the diagnostic and management challenges in resource-limited settings.
This study found that wavy sinus hairs in cats were significantly associated with feline leukemia virus infection, suggesting this physical trait might be useful for identifying infected cats.
9 citations
,
October 2010 in “Journal of the American Academy of Dermatology” Iron deficiency might cause hair loss, but better testing is needed.
2 citations
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December 2012 in “Acta Facultatis Medicae Naissensis” This article presents a case of syphilitic alopecia in a man, where treatment with benzathine penicillin G led to dramatic hair regrowth and resolution of syphilitic lesions within three months.
115 citations
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June 2004 in “Pediatrics” This study found that children are susceptible to SARS-CoV, with good short- to medium-term outcomes, and that sore throat and neutrophilia can predict severe illness.
6 citations
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December 2015 in “International journal of immunopathology and pharmacology” A novel mutation in the SLC39A4 gene was identified in an infant with mild, incomplete acrodermatitis enteropathic symptoms, suggesting genetic testing is beneficial even without the full symptom triad.
July 2022 in “Dermatologica Sinica” In this study, zinc deficiency, iron depletion, and thyroid abnormalities were commonly observed in female pattern hair loss patients, suggesting the benefit of testing for these conditions.
7 citations
,
July 2020 in “Journal of The American Academy of Dermatology” This article discusses the challenges of attributing skin manifestations to COVID-19, emphasizing the need for more studies to differentiate virus-specific lesions from nonspecific ones, and reports no new clinical results.
3 citations
,
October 2019 in “JAAD Case Reports” This review discusses different forms and patterns of alopecia associated with lupus erythematosus and reports no new clinical results; the authors highlight distinct features of these conditions.
May 1948 in “Journal of the American Medical Association” The reply suggests checking for false positive or asymptomatic syphilis and using penicillin for treatment if necessary.
May 2026 in “Ukrainian journal of veterinary sciences” In this study, researchers found that parasitic dermatitis in dogs is predominantly caused by ectoparasites like fleas and mites, with flea allergy dermatitis being particularly prevalent, and noted that diagnosis typically relies on laboratory methods, while treatments involve insectoacaricidal drugs and prevention strategies.
213 citations
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June 2017 in “Rheumatology” This guideline outlines the management of systemic lupus erythematosus in adults but reports no new clinical findings.
42 citations
,
June 2020 in “Seminars in Oncology” This article reviews sex disparities in COVID-19 outcomes and explores the influence of sex hormones on disease severity, but it reports no new results; further studies are ongoing.
18 citations
,
March 2009 in “Medical Hypotheses” This review discusses the potential link between long-term transdermal exposure to sex hormones from antiperspirants and increased breast and prostate cancer rates, calling for further research to confirm this theory.
May 2025 in “The Journal of Rheumatology” This case report describes a 32-year-old Filipino female with mixed connective tissue disease who sequentially developed distinct autoimmune disorders over seven years, highlighting the complexities in diagnosis and management of overlap syndromes.
32 citations
,
January 2015 in “Annals of diagnostic pathology” This study highlights the importance of recognizing oral lesions in diagnosing syphilis, as illustrated by three reported cases.
May 2025 in “The Journal of Rheumatology” This case report describes a 47-year-old woman with dilated cardiomyopathy as the first sign of primary antiphospholipid syndrome, highlighting the need for APS screening in similar patient presentations.
July 2014 in “Elsevier eBooks” The document concludes that various hypersensitivity diseases in horses can be diagnosed and treated with methods like immunotherapy and medication, and early aggressive treatment is crucial for severe diseases like equine cutaneous pythiosis.
35 citations
,
January 2019 in “Clinics in Dermatology” This review discusses contemporary issues in syphilis diagnosis and management, emphasizing the importance of recognizing and addressing both biomedical and psychosocial aspects, but provides no new clinical results.
22 citations
,
October 2019 in “International Journal of Nanomedicine” This study suggests that the hydrogel nanoparticle formulation of hair growth-promoting compounds may enhance hair follicle penetration and induce hair growth in tested models, demonstrating its potential as a hair growth treatment.
2 citations
,
January 2004 in “Elsevier eBooks” This article reviews historical uses of the term "lupus" for various skin disorders but provides no new clinical findings.
December 2025 in “Nature Communications” This study demonstrated that skin organoids derived from human stem cells can model cutaneous tuberculosis, revealing that fibrosis development in Mycobacterium tuberculosis-infected organoids is linked to the PI3K-AKT and AP1 pathways in fibroblasts, and suggesting the potential for antifibrotic treatment evaluation.
May 2018 in “International Journal of Advances in Medicine” This study reports the successful management of acute liver failure in a 25-year-old woman with concurrent Hepatitis B and autoimmune hepatitis, using a combination of steroids, azathioprine, and tenofovir disoproxil fumarate.
April 2012 in “Informa Healthcare eBooks” Alopecia areata is a common autoimmune condition causing varying hair loss, diagnosed by specific patterns of inflammation around hair follicles, with several treatment options available.
1 citations
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January 2013 in “Mayo Clinic Proceedings” This case study details a 31-year-old woman diagnosed with secondary syphilis that presented with chronic headaches and hair loss, ultimately attributed to neurosyphilis and alopecia syphilitica.
3 citations
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February 2022 in “Journal of Infection” In this study, healthcare workers with asymptomatic or mild SARS-CoV-2 infections had lower antibody titers and higher reinfection rates compared to those with more severe initial infections.