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A new syndrome was linked to two new genetic changes in the MBTPS1 gene in a 14-year-old girl.

Dutasteride treatment in men with mild to moderate COVID-19 reduced viral shedding, inflammation, and recovery time without serious side effects.

Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.

Proxalutamide significantly lowered hospitalization rates in women with mild-to-moderate COVID-19.

Acne patients have higher levels of mTOR in their skin, which could be linked to future metabolic disease.

VDR regulation varies by tissue and is crucial for its biological functions.

The protein EZH2 blocks microRNA-22, increasing STK40 protein, which helps hair follicle stem cells change and grow hair.

The ACE1 gene variant doesn't affect long-COVID symptoms.

Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.

Proxalutamide improved blood markers related to inflammation, immune response, and clotting in COVID-19 patients, potentially reducing hospitalizations.

The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.

Men with androgenetic alopecia and hypertension may experience more severe COVID-19.

Cysteine and arginine are essential for hair growth and thickness.

The calcineurin/NFAT pathway plays a significant role in the development and growth of a type of skin cancer called cutaneous squamous cell carcinoma.

Metformin helps hair growth by affecting cell signals related to hair follicle development.

Cyclosporine A slowly changes cell membranes, explaining some of its effects and side effects.

MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

GALT5 and GALT2 are important for plant growth and development because they help with protein glycosylation.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

Activin A helps heal skin wounds and protects the brain after injury.

Proxalutamide significantly lowered hospital admissions for male COVID-19 patients compared to a placebo.

Proxalutamide helps COVID-19 patients get rid of the virus faster and recover quicker.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

A specific protein complex increases the activity of a plant enzyme, but this action is not required for plant root hair growth.

P144® improves hypertrophic scars by reducing size and thickness and increasing elasticity.