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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

PI3K/Akt pathway is crucial for hair growth and regeneration.

CIP/KIP proteins help stop cell division and support hair growth.

The conclusion suggests a possible link between iron levels and hair health in women, recommending further research on iron supplementation for hair loss.

The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.

Women with high androgen levels may have more severe COVID-19 symptoms.

The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.

The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

15-lipoxygenase helps keep skin healthy by reducing inflammation.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.

Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.

Understanding glycans and enzymes that alter them is key to controlling hair growth.

Thymosin β4 helps improve skin healing and reduce scarring.

Mice with CBS deficiency are healthier on a low-methionine diet.

Sp6 promotes tooth development by reducing follistatin levels.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

COVID-19 can cause skin issues like chilblains and rashes, which may help in early detection, especially in patients without other symptoms.

High levels of auxin increase root hair growth by activating RSL2 and producing ROS, while high phosphate levels hinder growth by repressing RSL2.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

SCF and ET-1 together significantly increase skin pigmentation and melanin production.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.