40 citations,
April 2008 in “European journal of endocrinology” Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.
40 citations,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” S100A3 protein is crucial for hair shaft formation in mice.
39 citations,
May 2011 in “Human Immunology” Genetics play a role in acne, but how exactly they contribute is not fully understood.
39 citations,
April 2011 in “Recent Patents on Drug Delivery & Formulation” Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.
38 citations,
April 2016 in “Experimental Dermatology” The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.
38 citations,
January 2011 in “Endocrine Journal” Weight loss and metformin don't significantly change vaspin levels in women with PCOS.
38 citations,
December 2009 in “Therapeutic Advances in Medical Oncology” The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
37 citations,
March 1990 in “The Journal of Pediatrics” Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.
36 citations,
August 2018 in “Dermatologic Clinics” Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.
36 citations,
January 2018 in “Scientific reports” Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.
36 citations,
January 2017 in “Journal of Obstetrics and Gynaecology Research” The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.
34 citations,
March 2020 in “BMC plant biology” Graphene oxide and indole-3-acetic acid together inhibit root growth in Brassica napus L. by affecting multiple plant hormone pathways.
34 citations,
November 2010 in “Development” Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
33 citations,
September 2017 in “Journal of clinical immunology” New treatments for immune disorders caused by FOXN1 deficiency are promising.
33 citations,
June 2016 in “Pediatric Dermatology” Some congenital hair disorders improve in childhood or with treatments like minoxidil and retinoids, while others like Netherton syndrome and trichothiodystrophy have a poor prognosis.
33 citations,
September 2012 in “Wound Repair and Regeneration” Applying calreticulin can speed up wound healing in diabetics.
33 citations,
March 2006 in “Seminars in cutaneous medicine and surgery” The document explains how to identify different hair problems using a microscope.
32 citations,
February 2017 in “Oncotarget” Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
31 citations,
February 2021 in “Nutrients” Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.
31 citations,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
31 citations,
September 2006 in “International journal of gynaecology and obstetrics” New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.
31 citations,
January 2003 in “Dermatology” Steroidogenic isoenzymes may help improve treatments for common hair loss.
31 citations,
January 1981 in “Pharmacology & Therapeutics” Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.
30 citations,
October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
30 citations,
April 2017 in “European Journal of Cell Biology” CIP/KIP proteins help stop cell division and support hair growth.
30 citations,
October 2010 in “Journal of The American Academy of Dermatology” The conclusion suggests a possible link between iron levels and hair health in women, recommending further research on iron supplementation for hair loss.
30 citations,
May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.
29 citations,
October 2020 in “Journal of the European Academy of Dermatology and Venereology” Women with high androgen levels may have more severe COVID-19 symptoms.
29 citations,
April 2020 in “Biomolecules” The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
29 citations,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.