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Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Keratins are crucial for cell structure, growth, and disease risk.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Restoring hair bulb immune privilege is crucial for managing alopecia areata.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.