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This study introduces a co-design framework using finite element analysis to optimize separable bubble microneedles, demonstrating enhanced transdermal and sublingual drug delivery in preclinical models. In vivo results showed faster hair regrowth and glucose lowering in animals, indicating potential improvements over traditional methods.

This study found that finite element analysis-guided design improved bubble microneedles' controlled tip separation and insertion strength, supporting effective transdermal and sublingual drug delivery.

This study developed a co-design framework using finite element analysis to optimize bubble microneedles, achieving controlled tip separation and effective drug delivery through the skin and mucosa while maintaining insertion strength.

In this study, microneedle-assisted delivery of polyglutamate significantly improved hair parameters, scalp symptoms, and quality of life in androgenetic alopecia patients, with no serious adverse reactions reported.

This study found that pretreating mouse skin with microneedles significantly enhanced the hair growth inhibitory effect of eflornithine cream, likely by improving its skin permeation.

This review highlights the potential of nanotechnology for hair follicle regeneration, focusing on strategies such as hair cycle modulation, progenitor cell stimulation, and wound-induced hair neogenesis, while also discussing regulatory challenges that may affect the development of these innovative approaches.

This review discusses the potential of extracellular vesicles for facial aesthetic applications, including scar reduction and skin rejuvenation, but reports no new clinical results; further research into production and mechanisms is needed.

This case series observed that the combination of platelet-rich plasma and fat grafting improved hair quality and density in patients with non-scarring alopecia, with effects visible by 12 weeks and sustained up to one year.

PRP treatment satisfies 58% of female hair loss patients, with most noticing fuller, thicker hair and less shedding.

In this study, PRP treatment improved hair loss in 40 female patients with female pattern alopecia, with most progressing to better grades of hair coverage after 6 months, while only minor pain was occasionally reported as an adverse effect.

This review discusses photothermal agent hybrids in hydrogels for antibacterial action, angiogenesis, and osteogenesis in tissue engineering, but reports no new experimental findings.

This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.

This review discusses the potential of adipose-derived tissue components like nanofat and stem cells for aesthetic rejuvenation, covering their use in hair growth, scar reduction, and more, without reporting new clinical results.

This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.

Invasomes effectively deliver drugs through the skin and have potential for improved treatments.

This review discusses novel treatments for androgenetic alopecia, including therapies like platelet-rich plasma and adipose-derived stem cells, and reports no new clinical results.

This study found that 448-kHz Capacitive-Resistive Electrothermal Therapy led to a significant increase in hair density in women with Female Pattern Hair Loss, likely due to stimulated proliferation of dermal papilla cells.

This study found that excipients significantly influence the effectiveness of curcumin nanocrystals in dermal applications, enhancing or hindering hair follicle targeting and passive diffusion based on their selection.

This review highlights the potential of hydrogels in veterinary medicine, emphasizing their advantages over traditional wound dressings and their promising applications in drug delivery and tissue engineering, despite currently limited use in this field.

In this phase I/II clinical trial, placenta-derived mesenchymal stem cell exosome therapy significantly improved hair density and diameter, and reduced hair loss in patients with androgenetic alopecia, though further large-scale studies are needed to confirm these results and investigate the underlying molecular mechanisms.

This review discusses the use of platelet-rich plasma in various dermatological applications and reports no new clinical results; the authors call for more rigorous trials to confirm its effectiveness.

This review indicates that most studies reported positive effects of platelet-rich plasma injections for treating androgenic alopecia, with no major side effects, suggesting it may be a safe alternative to Minoxidil and Finasteride.

Cosmetics enhance beauty, fix defects, and intimidate enemies, with varying cultural standards and alternative methods.

This study found that dexamethasone-loaded Eudragit® L 100 nanoparticles displayed controlled drug release depending on pH levels, with minimal toxicity to human fibroblasts.

In this study, researchers developed a wearable red and blue LED patch and a sprayable fibrin gel to treat infected wounds at home, demonstrating effective infection control and enhanced wound healing in diabetic mice and minipigs.

This review discusses the use of platelet-rich plasma for various dermatological conditions and highlights the need for more research to standardize its protocols and understand its biological mechanisms.

This review summarizes the positive clinical response of using platelet-rich plasma as an adjuvant in skin rejuvenation treatments, with no identifiable complications, suggesting a promising outlook for its future use.

In this study, researchers administered eight sessions of intradermal injections containing growth factors into the scalp of 1000 patients, reporting a significant reduction in hair fall in 83% of participants and increased total hair count and shaft diameter, with promising tolerance and safety.

This study reported that while topical minoxidil exhibits hair regrowth in androgenetic alopecia, oral minoxidil 5 mg/day was more effective than topical forms after six months, with low doses also potentially effective for women and other hair loss types.

In this study, applying deer antler velvet extract-loaded niosomes and microspicules serum to the scalp significantly improved hair growth, melanin content, and skin hydration over 14 to 30 days without causing skin irritation.