143 citations
,
May 2002 in “PubMed” This study found that the retinoid LGD1069 suppressed mammary tumorigenesis in a mouse model without observable toxicity, while TTNPB showed modest effects but was associated with significant toxicity.
137 citations
,
April 2015 in “Nature Reviews Molecular Cell Biology” This review discusses the distinct roles and surprising developmental flexibility of multiple somatic stem cell types in tissue maintenance and repair, reporting no new results but highlighting emerging questions about their regulation and origins.
136 citations
,
February 2017 in “International Journal of Molecular Sciences” This study observed that autologous platelet-rich plasma treatment improved hair count and density in areas with androgenetic alopecia compared to placebo, with differing outcomes based on the PRP collection device used.
91 citations
,
July 2010 in “Tissue Engineering Part A” This study found that low oxygen conditions and ECM degradation products increased the proliferation and migration of perivascular stem cells without altering their phenotype, suggesting potential roles in tissue repair.
54 citations
,
July 1994 in “Journal of Dermatological Science” This study found that topical application of FK506 stimulated hair growth in animals, which may occur independently of its immunosuppressive effects, though its effect on human hair growth remains unclear.
54 citations
,
July 1967 in “Science” This study found that aged tritiated thymidine breaks down and incorporates into cytoplasmic macromolecules, not DNA, suggesting caution in its use.
53 citations
,
October 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that cyclophosphamide induced significant keratinocyte apoptosis in anagen hair follicles of mice, while topical calcitriol-analogs reduced this apoptosis, suggesting a protective effect against chemotherapy-induced alopecia.
45 citations
,
December 2004 in “Forensic Science International” This study reports that using laser microdissection to isolate telogen hair follicles significantly improves DNA extraction efficiency for STR typing, reducing contamination from keratin.
36 citations
,
October 2000 in “British Journal of Dermatology” This study identified a distinct gene near the hairless locus on chromosome 8p that is responsible for hereditary Marie Unna type hypotrichosis in a German family.
27 citations
,
February 2009 in “Autoimmunity Reviews” This study describes the development of the EUSCLE Core Set Questionnaire for cutaneous lupus erythematosus, designed to standardize data collection, facilitate epidemiological analysis, and guide diagnostic and therapeutic strategies across European centers.
22 citations
,
December 2007 in “Dermatologic Surgery” This study found that dermatology leads in performing office-based cosmetic procedures compared to other specialties, with a focus on white, female patients aged 40 to 59.
19 citations
,
May 2020 in “Cells” This study found that 5% primed conditioned medium from human umbilical cord blood-derived mesenchymal stromal cells significantly improved hair density, thickness, and growth rate in patients with androgenetic alopecia.
19 citations
,
June 2009 in “Seminars in cutaneous medicine and surgery” This article discusses diagnostic challenges and management approaches for hair loss in women of color, emphasizing the importance of clinical examinations and education to prevent and manage traction alopecia.
18 citations
,
January 2001 in “Annual Reports in Medicinal Chemistry” This chapter reviews selective androgen receptor modulators, discussing their therapeutic potential beyond current androgen applications, and reports no new clinical findings.
15 citations
,
July 2002 in “Australasian Journal of Dermatology” In this case report, two plywood mill workers developed allergic contact dermatitis due to exposure to uncured phenol-formaldehyde resin, not sawdust as initially suspected.
15 citations
,
August 1989 in “Archives of Dermatology” This article hypothesizes that minoxidil may act as an endothelium-derived relaxing factor agonist, which could explain both its vasodilatory properties and its potential effect on hair growth; however, it reports no new experimental results.
14 citations
,
August 2014 in “Applied Physiology, Nutrition, and Metabolism” This study concluded that an 8-week low-starch/low-dairy diet increased fat oxidation in overweight and obese women with PCOS.
10 citations
,
June 2011 in “Movement Disorders” THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.
10 citations
,
May 2009 in “Journal of The American Academy of Dermatology” This case report describes a dual transposition flap technique for closing large scalp defects post-Mohs surgery, achieving minimal alopecia and scar visibility, though it is based on a single patient.
8 citations
,
October 2024 in “Frontiers in Cell and Developmental Biology” This review suggests that telocytes in male reproductive organs help organize tissue structure and paracrine factors, impacting organ development and pathology, but more research is needed on their molecular pathways.
8 citations
,
March 2023 in “Journal of Clinical Epidemiology” This updated guidance from the GRADE working group addresses issues with assessing inconsistency in treatment effect estimates and evaluating the credibility of effect modifiers in systematic reviews.
7 citations
,
August 2016 in “Nursing for Women's Health” This article reviews the issue of hair-thread tourniquets in infants, emphasizing the importance of awareness for timely diagnosis and suggesting prevention strategies, but reports no new clinical results.
6 citations
,
May 2007 in “Forensic Science Medicine and Pathology” This study found that Minoxidil can interfere with hair drug analysis for cocaine by producing peaks that obscure the detection of cocaine and its metabolites in chromatograms.
6 citations
,
January 2001 in “Dermatologic Surgery” This study observed that female androgenetic alopecia is common among Caucasian women, starting in the late 20s and peaking after age 50.
5 citations
,
June 2022 in “Scientific Reports” This study observed that basal cell carcinoma on the scalp shares more similar characteristics with truncal lesions than facial lesions, despite the scalp's proximity to the face.
5 citations
,
December 2018 in “Frontiers in Endocrinology” This study found that nuclear androgen receptor expression was enhanced by dihydrotestosterone in rat gubernacular mesenchyme, but this did not affect muscle morphology or matrix composition during fetal development.
5 citations
,
January 2015 in “Evidence-based complementary and alternative medicine” The authors concluded that the combination of 755 nm alexandrite laser and topical licorice is more effective than the alexandrite laser alone in reducing idiopathic hirsutism in women, with no serious adverse reactions reported.
5 citations
,
February 2013 in “Journal of Liquid Chromatography & Related Technologies” This study developed and validated a micellar electrokinetic chromatography method to determine finasteride stability, finding that the drug degrades under acidic, basic, and oxidative stress conditions.
5 citations
,
February 2004 in “Clinical and Experimental Ophthalmology” This study presents two cases correlating the clinical appearance of adult-onset foveomacular vitelliform dystrophy with optical coherence tomography findings, describing the location of the yellow vitelliform material.
4 citations
,
January 2016 in “JAMA Dermatology” This article discusses potential benefits of increasing active range of motion in the care of venous leg ulcers but reports no new clinical results.