October 2024 in “Endocrinology Insights” In this study, researchers found that both the EU-TIRADS and Bethesda systems exhibited high specificity but suboptimal sensitivity for predicting thyroid nodule malignancy in patients who underwent surgery, with Bethesda system showing particularly high specificity in this postoperative population.
This report presents a rare case of lichen spinulosus in a 52-year-old woman, featuring hyperkeratotic follicular papules and a dense lymphohistiocytic infiltrate in affected skin areas.
39 citations
,
May 2019 in “Journal of the American Academy of Dermatology” This study found that nonscarring alopecia in patients with systemic lupus erythematosus may indicate higher disease activity, as evidenced by specific histological and immunofluorescence changes.
March 2009 in “European Urology Supplements”
April 2018 in “Journal of Investigative Dermatology” This study found that DC-HIL+ myeloid derived suppressor cells are increased in the blood and skin of patients with cutaneous lupus erythematosus and show immunosuppressive properties.
September 1997 in “Journal of The European Academy of Dermatology and Venereology” Skin lymphoproliferative disorders are hard to diagnose and often linked to systemic diseases, but most have a good prognosis with accurate diagnosis.
18 citations
,
April 2014 in “Stem cells” The researchers reported that minor salivary gland stem cells exhibit stem cell characteristics and respond to tobacco-derived carcinogens, implicating the transforming growth factor beta pathway in their maintenance.
December 2024 in “Veterinary Dermatology” This case report identified cutaneous epitheliotropic T-cell lymphoma in a 3-year-old male sugar glider after skin biopsies, highlighting the need for thorough diagnostic evaluations in exotic pets.
February 2026 in “Dermatology and Therapy” This study observed that sonidegib led to a meaningful clinical response in a real-world Chinese cohort with locally advanced basal cell carcinoma, although pathological biopsy remains essential to confirm tumor clearance due to false positives in noninvasive assessments.
April 2017 in “Journal of Investigative Dermatology” This study suggests that sirolimus and propranolol may reduce abnormal lymphatic endothelial cell proliferation in lymphatic malformations, potentially improving vessel function and patient outcomes.
24 citations
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January 2019 in “Theranostics” This study found that loss of the Pten gene in Lgr5+ hair follicle stem cells promoted squamous cell carcinoma formation through the Akt/β-catenin signaling pathway.
2 citations
,
September 2017 in “Journal of Investigative Dermatology” This study found that notch1 signaling is severely impaired in hidradenitis suppurativa patients with or without NCSTN or other gamma-secretase gene mutations, highlighting a canonical defect at the lesional tissue level.
April 2024 in “JEADV Clinical Practice” This study suggests that establishing international consensus guidelines for including concealed or sensitive sites in routine forensic examinations is crucial to clarify clinician responsibilities, guide patient expectations, and reduce potential medicolegal issues.
3 citations
,
December 1989 in “PubMed”
10 citations
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July 2021 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” This study found that the expression of LRIG1 in Merkel cell carcinoma tumors was associated with improved overall and cancer-specific survival.
1 citations
,
September 2023 in “Journal of the American Academy of Dermatology”
25 citations
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December 2018 in “Human Molecular Genetics” This study found that the PSEN1-P242LfsX11 mutation in hidradenitis suppurativa influences cytokine and chemokine expression in macrophages, potentially affecting inflammatory responses.
March 2019 in “Journal of medical science and clinical research” This study found that cutaneous manifestations, including specific skin lesions and oral ulceration, are common early indicators of SLE and may aid in its diagnosis and management.
10 citations
,
February 2019 in “The New England Journal of Medicine” This abstract discusses the importance of controlling visible abdominal tumors in women with ovarian cancer to improve survival, and notes that nonvisible microscopic tumors are then targeted with chemotherapy; it reports no new results.
28 citations
,
June 2021 in “Frontiers in immunology” This review discusses the role of the long form of thymic stromal lymphopoietin in cutaneous immune-mediated diseases and reports no new results.
August 2024 in “Case Reports in Ophthalmology” In this case report, researchers observed that local radiation therapy to the orbits may not be sufficient to halt progression of new retinal lesions in older patients, even when the disease initially appears confined to the intraocular space.
9 citations
,
March 2017 in “Journal of Visualized Experiments” This study introduced a novel in vitro murine assay using transgenic mice to identify immunomodulatory compounds, which identified 160 potential hits from 4,398 compounds screened.
1 citations
,
November 2015 in “Journal of Evolution of Medical and Dental Sciences” This study observed that certain skin symptoms in SLE, such as malar rash and photosensitivity, are linked to systemic involvement, indicating their potential role as markers for disease activity.
28 citations
,
October 1984 in “Journal of Investigative Dermatology”
5 citations
,
September 2015 in “Journal of The American Academy of Dermatology” This letter highlights that the effectiveness of skin self-photography for melanoma detection has not been evaluated, although it could be a cost-effective option for patients without access to professional skin photography.
15 citations
,
September 2014 in “JAMA Dermatology” This discussion highlights the use of minimal incision extraction for lipoma removal, noting that it is a favored technique among dermatologists due to its efficiency, despite some hesitance with larger lipomas.
October 2017 in “Data Archiving and Networked Services (DANS)” This thesis found that in lupus nephritis, traditional classification criteria may not apply to patients with glomerular deposits without clinical SLE, indicating distinct prognostic and diagnostic challenges.
May 2024 in “International journal of medicine and psychology.” This study examined monoclonal antibodies LT-1, LT-2, and LT-7, finding they can effectively detect certain antigens on T and B cells involved in various lymphoproliferative diseases, aiding in the diagnosis of both acute and chronic lymphoid neoplasias.
October 2023 in “Indian Journal of Skin Allergy” This study discusses a rare case of subacute cutaneous lupus erythematosus induced by nab-paclitaxel, a complication scarcely reported in existing literature related to paclitaxel use.
9 citations
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October 2008 in “British Journal of Dermatology” This case report describes a patient with primary cutaneous natural killer/T-cell lymphoma, nasal type, where monoclonal Epstein–Barr virus genome expansion was associated with terminal aggressive behavior after an indolent clinical course.