research Targeting the Janus Kinase Family in Autoimmune Skin Diseases
Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
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60-90 / 440 results research Structural Mechanism of TRPV3 Channel Inhibition by the Plant-Derived Coumarin Osthole
Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
research Impact of Combined Baricitinib and FTI Treatment on Adipogenesis in Hutchinson-Gilford Progeria Syndrome and Other Lipodystrophic Laminopathies
Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research The Multisystem Impact of Long COVID: A Comprehensive Review
Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.
research The Coenzyme A Precursor Pantethine Enhances Antitumor Immunity in Sarcoma
Pantethine may boost the immune system's ability to fight sarcoma.
research Development of Gene Therapy for Inner Ear Disease: Using Bilateral Vestibular Hypofunction as a Vehicle for Translational Research
Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.
research Stress Exposure Modulates Peptidergic Innervation and Degranulates Mast Cells in Murine Skin
Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.
research The Role of Nrf2 in Hearing Loss
Activating Nrf2 can help protect against hearing loss.
research Modulating Mechanosensory Afferent Excitability by an Atypical mGluR
A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.
research Functional Complexity of Hair Follicle Stem Cell Niche and Therapeutic Targeting of Niche Dysfunction for Hair Regeneration
Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
research Hairy Tale of Signaling in Hair Follicle Development and Cycling
Hair growth and development are controlled by specific signaling pathways.
research Resident Stem Cells in Skin
Skin stem cells can help improve skin repair and regeneration.
research Effects of RF Electric Currents on Hair Follicle Growth and Differentiation: A Possible Treatment for Alopecia
RF-based therapies might help treat hair loss.
research Cluster Headache: Acute and Prophylactic Therapy
Sumatriptan injections, high-flow oxygen, and verapamil effectively treat cluster headaches.
research Problems of Creating Scientific Ideas About World Development
Continuous research and innovative strategies are essential for sustainable development.
research Use of H-1 Antihistamine in Dermatology: More Than Itch and Urticaria Control: A Systematic Review
H-1 antihistamines may help with various skin conditions, but more research is needed to confirm their effectiveness.
research An Advanced Review: Polyurethane-Related Dressings for Skin Wound Repair
Polyurethane dressings show promise for wound healing but need improvements to adapt better to the healing process.
research The Pharmacologic Treatment of Muscle Pain
The document concludes that more research is needed to understand how to treat muscle pain with drugs.
research Transgender and Migraine: Impact of Hormone Therapy
Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.
research Phase-Specific Differential Regulation of Mechanical Allodynia in a Murine Model of Neuropathic Pain by Progesterone
Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.
research Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives
Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
research Steroid 5α-Reductase 2 Deficiency Leads to Reduced Dominance-Related and Impulse-Control Behaviors
Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
research Hair Growth-Promoting Activity of Hot Water Extract of Thuja Orientalis
Thuja orientalis hot water extract may help hair grow by starting the growth phase and improving hair follicle development.
research The Biology and Clinical Application of Systemic Glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
research Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice
A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.
research The Role of AUTS2 in Neurodevelopment and Human Evolution
The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
research Pregnenolone for the Treatment of L-DOPA-Induced Dyskinesia in Parkinson's Disease
Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.
research Blue Screen – Blue Mood? Influence of Background Color and Attractiveness of Female Stimulus Persons on Current Mood in an Online Experiment (PANAS)
Attractive women slightly worsened mood, green backgrounds improved mood, and older people had better moods.