October 2021 in “Cosmoderma” This review summarizes existing knowledge on diffuse and patterned alopecia, emphasizing recent advancements in treatment beyond FDA-approved options, but it reports no new clinical findings.
October 2020 in “Authorea (Authorea)” This review discusses the influence of androgens on opioid-mediated effects and calls for further research into their role in sex differences and potential therapeutic options for chronic pain and substance use disorders.
May 2019 in “Clinica chimica acta” This study reported that mice with more diverse gut microbiota showed higher hair levels of certain hormones and 1-AG compared to those with less diverse microbiota, though plasma differences were more complex and varied by stress and sex.
December 2018 in “International journal of women’s dermatology” This case report highlights that frontal fibrosing alopecia may be underrecognized in young women and notes that no single treatment regimen has been proven consistently effective for this condition.
January 2016 in “Georg Thieme Verlag eBooks” The document recommends personalized, culturally sensitive treatments to rejuvenate the aging Asian face, focusing on natural results and specific techniques for skin, hair, and facial features.
May 2015 in “Journal of Investigative Dermatology” Melanoma risk tools need improvement, a gene mutation causes a hair disorder that might be treated by managing cell stress, a potential therapy for a skin-ear disorder involves blocking cell channels, skin wrinkling may indicate lung aging regardless of smoking, and oxidative stress might contribute to common baldness.
April 2015 in “Experimental Dermatology” Melanoma risk tools need improvement, certain gene mutations cause skin diseases and could be treated by targeting those mutations, skin wrinkling may relate to lung aging due to genetic factors, and oxidative stress affects hair loss but can be reduced in low oxygen.
September 2012 in “European journal of psychotraumatology” This study presents a new LC-MS/MS method that allows for more accurate detection of seven steroid hormones in human hair, enhancing the specificity and reliability of hormone analysis in psychoneuroendocrinological research.
March 2010 in “Gynecologic and Obstetric Investigation” This review discusses various aspects of hirsutism in women, including causes, hormonal influences, and treatment approaches, but reports no new findings.
January 2008 in “US endocrinology” This paper describes the hGRα gene structure and its expression, focusing on the functional properties of the longest GRα isoform, but reports no new results.
November 2006 in “評価・診断に関するシンポジウム講演論文集” This study found that KSR1 is essential for v-Ha-ras-mediated skin tumor formation in mice but not for MT-driven mammary tumor genesis, suggesting its potential as a therapeutic target in Ras/MAPK signaling.
January 2001 in “Clinical and Experimental Dermatology” A test for nail fungus was most accurate with PAS stain, low-dose spironolactone helped two-thirds of acne patients, metformin reduced symptoms of HIV-related fat distribution changes with some side effects, and skin examination with dermoscopy was better at detecting abnormal moles, while temporary tattoos can cause skin reactions.
January 2000 in “Time to knit” This article describes the extraction and characterization method for wedelolactone from Eclipta alba but presents no new clinical results.
August 1998 in “Dermatologic Surgery” Use steroid creams without parabens and educate on hair transplant techniques to improve cosmetic surgery outcomes.
This study developed a sensitive method for assessing hair keratin stretch elasticity modulus, suggesting potential applications in forensic medicine.
March 1997 in “The Lancet” Hirsutism is abnormal male-pattern hair growth in females due to excess androgens.
January 1995 in “Journal of the Society of Cosmetic Chemists” This study found no conclusive evidence of biocatalytic activity of guinea pig liver transglutaminase with virgin human hair, potentially due to a fatty acid layer on the hair surface.
November 1993 in “PubMed” This review discusses causes and treatments for hirsutism in women and reports no new clinical results.
September 1976 in “PubMed” This article discusses the causes and treatments for hirsutism, concluding that reverse-sequence therapy with cyproterone acetate and ethinyl estradiol is effective for severe cases but has cost and side effects.
December 2019 in “International journal of pharmaceutical quality assurance” This study developed and validated a sensitive and accurate UV spectrophotometric method for estimating finasteride concentrations, showing reliable results within a range of 5–25 μg/mL.
April 2018 in “Selçuk Üniversitesi Tıp Fakültesi dergisi” This study found that repeated PRP injections in patients with androgenetic alopecia may lead to hyperalgesia, where pain is felt with less stimulus after each treatment.
June 2017 in “Journal of The European Academy of Dermatology and Venereology” This meta-analysis found that patients with androgenetic alopecia have an atherogenic lipid profile, with higher LDL, triglycerides, and total cholesterol, and lower HDL, potentially explaining increased cardiovascular risk.
April 2009 in “11th European Congress of Endocrinology” Taking 1 mg finasteride for a year reduces dihydrotestosterone levels in men with early hair loss, but doesn't change their metabolic state.
December 1990 in “PubMed” This article discusses the role of androgens in causing hirsutism and male pattern baldness in women and emphasizes the need for antiandrogen treatment to manage these conditions, without reporting new clinical results.
January 2024 in “Regenerative Biomaterials” This review introduces the potential of metal-organic framework-based functional composite materials in tissue engineering but reports no new results, emphasizing the need for further innovation in the field.
1231 citations
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May 2001 in “Hypertension” This review discusses the potential mechanisms by which androgens may elevate blood pressure, particularly through impacts on the renin-angiotensin system, but reports no new experimental results.
514 citations
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February 2011 in “International journal of women's health” This review discusses treatments for various symptoms of polycystic ovary syndrome, including lifestyle changes, medical, and surgical interventions, but does not present new clinical results.
450 citations
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January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This article reviews follicular melanogenesis, detailing how melanin synthesis and its regulation in hair follicles depend on a complex interplay of cellular and molecular mechanisms, but reports no new clinical findings.
253 citations
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April 2008 in “Current opinion in cell biology” This study found that Notch signalling promotes differentiation of epidermal cells and acts as a tumour suppressor in the skin by interacting with various pathways and mechanisms.
216 citations
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November 1999 in “Fertility and Sterility” This study found that a basal 17-hydroxyprogesterone level is effective for screening nonclassic adrenal hyperplasia in women, with a 4 ng/mL cutoff providing high specificity and positive predictive value.