April 2017 in “InTech eBooks” This review discusses potential mechanisms and treatments for trichodynia, noting a lack of strong literature support and reporting no new clinical results; the authors highlight several hypotheses and available treatment options.
16 citations
,
June 2019 in “International Journal of Women's Dermatology” This study found that type 2 diabetes was associated with a higher risk of severe central scalp hair loss in African American women.
12 citations
,
June 2010 in “Journal of dermatology” This study found that hyperpigmentation following contact immunotherapy for severe alopecia areata may indicate poor treatment responsiveness and aligns with characteristics of pigmented contact dermatitis.
5 citations
,
January 2014 in “Hospital pharmacy” This case report suggests that frequent application of diphenylcyclopropenone 2% solution to the scalp for alopecia areata may lead to scalp angioedema.
July 2018 in “Elsevier eBooks” This review discusses various causes and treatments of scalp pruritus, distinguishing between conditions with primary skin lesions and those without, but provides no new clinical results.
74 citations
,
January 2020 in “IEEE Access” This study reports that the ScalpEye system accurately diagnosed dandruff, folliculitis, hair loss, and oily hair with a precision range of 97.41% to 99.09%.
October 2025 in “Current Pharmaceutical Research” This study evaluated a new herbal shampoo made from traditional plants and found it to have effective cleansing properties, moderate foam stability, and environmental safety, suggesting it as a favorable natural alternative to synthetic shampoos.
245 citations
,
March 2012 in “Journal of The American Academy of Dermatology” This review discusses the dermoscopic features of common hair and scalp disorders and reports no new clinical results, aiming to assist dermatologists in diagnosing conditions like tinea capitis and alopecia areata.
65 citations
,
October 2018 in “Frontiers in cellular and infection microbiology” This study observed that dandruff in Indian women is associated with a distinct scalp microbiome, including specific bacterial and unknown Malassezia species, with implications for nutrient homeostasis and cell-host adhesion pathways.
30 citations
,
January 2014 in “Annals of Dermatology” This study observed no significant relationship between trichoscopic findings and disease severity in male or female androgenetic alopecia, despite some specific patterns correlating with different severity levels in female patients.
25 citations
,
November 1987 in “British Journal of Dermatology” This study observed increases in scalp blood flow following the application of 3% minoxidil and 0.1% hexyl nicotinate in individuals with alopecia.
15 citations
,
January 2017 in “Lasers in Surgery and Medicine” In this study, four male patients with extensively photodamaged scalps showed a 60-90% improvement in dyspigmentation, lentigines, and keratosis after a single treatment with the fractionated 1,927 nm thulium fiber laser, with no adverse events observed.
6 citations
,
January 2015 in “Dermatology” This review covers trichoscopy's role in diagnosing scalp disorders, emphasizing its potential to improve clinical accuracy, but it reports no new clinical results.
5 citations
,
May 2021 in “International Journal of Cosmetic Science” This review discusses the evidence for a cause-and-effect relationship between scalp condition and hair condition, and reports no new clinical results from trials.
4 citations
,
May 2021 in “Lasers in Surgery and Medicine” This study observed that adding low-level light therapy with the GentleWaves® device to Minoxidil significantly boosted hair regrowth in men with androgenetic alopecia by reducing scalp inflammation.
4 citations
,
January 2021 in “Skin appendage disorders” In this study, researchers found that washing hair 5–6 times per week results in higher satisfaction and better objective and subjective hair and scalp conditions among Asian populations, with no observed detrimental effects from frequent washing.
1 citations
,
January 1967 in “The BMJ” The document concludes that while some hair and scalp disorders can be treated, hair loss from destroyed follicles is permanent, and damaged hair can only regrow naturally.
This study found that patients with androgenetic alopecia showed distinct scalp bacterial imbalances compared to healthy individuals, which were associated with unhealthy lifestyles. These microbial changes might contribute to follicular inflammation, potentially accelerating hair loss in these patients.
July 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” In this review, researchers examined the concentration of cortisol in scalp hair of individuals with alopecia areata to explore its relationship with disease variables, as cortisol in hair can indicate chronic stress, which may impact alopecia areata pathogenesis.
January 2017 in “Springer eBooks” The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.
Infliximab was effective in treating a scalp condition that did not respond to other treatments.
52 citations
,
December 2000 in “Archives of Dermatological Research” This study found that the stratum corneum of scalp skin in humans has distinct functional characteristics compared to the facial skin and volar forearm, including higher hydration levels and intermediate epidermal turnover rates.
1 citations
,
May 2015 in “Journal of evolution of medical and dental sciences” In this study, a notable number of dermatology outpatients were found to have incidental scalp findings, indicating the importance of examining the scalp during clinical evaluations.
March 2025 in “Pain Physician” This retrospective study found that applying local skin precooling before scalp nerve block significantly reduced injection site pain during PRP mesotherapy for patients with androgenetic alopecia, compared to those who did not receive precooling, thus improving patient comfort and compliance.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the occipital scalp had significantly higher epidermal nerve fiber density than the frontoparietal scalp, which may explain increased sensitivity in some patients.
227 citations
,
January 1998 in “Journal of Endocrinology” This study found that dermal papilla cells from balding scalp hair follicles have significantly higher levels of androgen receptors than those from non-balding follicles, supporting their in vivo androgen response.
196 citations
,
March 2016 in “Nature Communications” In this study, researchers identified 18 genetic associations with scalp and facial hair traits in Latin Americans, including novel loci for hair greying and balding, with implications for understanding hair evolution.
104 citations
,
August 2008 in “Clinics in Dermatology” This review discusses current treatment challenges and strategies for managing psoriasis in the scalp, nails, and intertriginous areas, emphasizing the need for effective and well-tolerated long-term options, but reports no new clinical results.
46 citations
,
April 2009 in “Journal of Dermatological Case Reports” This study established standard trichoscopy norms for adult white females, providing benchmarks for hair thickness, percentage of thin hairs, and pilosebaceous units with single hair across different scalp areas.
46 citations
,
December 2003 in “Advances in neonatal care” This article reviews fetal scalp hair formation and related disorders but reports no new research results.