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The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Hair follicles help attract immune cells to the skin during stress.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

GPRC5D is linked to the formation of hair, nails, and certain tongue areas.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.

Radiation damages salivary glands by harming blood vessels, but antioxidants might help protect them.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

TGase 3 helps build hair structure by forming strong bonds between proteins.

Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.

Using low-dose IL-2 to increase regulatory T cells might be a safe way to treat type 1 diabetes without severe side effects.

The guidelines help doctors manage skin problems from certain cancer treatments to improve patients' lives.

More research is needed on the health effects of hormone therapy for transgender and nonbinary people.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Botulinum and tetanus neurotoxins are better understood now, with updated information on their effects and treatment.

Pigs in farrowing crates and loose-housing systems showed no difference in chronic stress levels as measured by hair cortisol.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

There is a significant need for better-validated quality of life tools in dermatology.

Skin problems are common in lupus patients and should be treated early to prevent worsening.

Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.

Some vitamins and minerals are important for preventing hair loss, but treating hair loss with them without a known deficiency is not proven effective.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Shallot extract may help with hair growth and treating hair loss.

Autophagy helps keep skin healthy and may improve treatments for skin diseases.

A new small peptide may help hair growth by activating a specific receptor and should be tested in humans.

Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.