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Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Finasteride effectively treats baldness but may cause sexual side effects.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Flutamide rarely causes liver toxicity in prostate cancer patients.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Minoxidil boosts hair growth by activating PGHS-1.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

New treatments for male hypogonadism are effective and should be personalized.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Oral finasteride works better than topical minoxidil for hair growth, both are safe.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Products should be called 'sperm-safe' only after thorough, well-designed tests.