Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses epidermal stem cell diversity, revealing previously unrecognized differences in stem cell populations, but reports no new experimental results; it highlights the need for further exploration of stem cell interactions and quiescence.

This review discusses the various stem cell populations associated with hair follicles and their potential in regenerative medicine, highlighting differences between murine and human hair follicles but reports no new clinical results.

This review explores the role of TGF-β superfamily pathways in stem cell environments and their implications for tissue regeneration and cancer development, reporting no new experimental results.

This study found that the transcription factor Gata6 regulates the sebaceous duct lineage identity and plays a crucial role in epidermal wound healing by enabling dedifferentiation and broader lineage capabilities in post-mitotic cells.

This review discusses the diverse roles and characteristics of epidermal and dermal stem cells in skin regeneration and aging, highlighting their potential applications in regenerative medicine and reports no new clinical results.

This review discusses the roles of TGF-β family signaling in regulating normal and cancer stem cells and highlights the need for further research to develop potential cancer treatments; it reports no new results.

This review discusses the similarities and differences between normal stem cell proliferation and cancer cell oncogenesis and concludes that understanding these mechanisms could improve cancer treatment strategies, but it reports no novel findings.

This study reports that human eccrine sweat gland cells are capable of forming a stratified epidermis, suggesting they may serve as an additional source of keratinocytes for skin repair.

This review highlights recent advances in chitosan-based nanoparticles (CS NPs) for drug delivery, discussing their modifications, preparation methods, production with organic and inorganic materials, and their latest implementations in the field, emphasizing the role of CS NPs in improving drug transport and release properties.

This article describes protocols for isolating and expanding human epidermal neural crest stem cells and discusses their potential for cell-based therapies in regenerative medicine, but reports no new clinical results.

In this study, older men using 5α-reductase inhibitors for prostatic enlargement did not show increased risk of suicide, but had elevated risks of self-harm and depression.

This study found that patients with alopecia perceive their hair loss as more severe than dermatologists do, and their own ratings of hair loss severity better reflect their quality of life impacts.

This review discusses the clinical features and therapeutic goals for teenagers with PCOS, emphasizing the need for further research into its causes and potential long-term health risks, but reports no new clinical results.

This review assesses the benefits and limitations of various supramolecular hydrogels, including polymeric and peptide-based types, for wound healing, but reports no new clinical results.

COVID-19 may cause a temporary hair loss condition called telogen effluvium in some patients after recovery.

This review highlights recent advances in understanding how the extracellular matrix regulates epidermal stem cell fate, emphasizing the importance of the hair follicle stem cell niche, but reports no new empirical findings.

This study found that human hair follicle-derived mesenchymal stem cells maintained their proliferation and differentiation potential when cultured with acidic fibroblast growth factor, basic fibroblast growth factor, or epidermal growth factor.

This study found that bleach treatments significantly increased hair surface roughness and decreased Young's modulus, indicating marked changes in hair's molecular structure which may affect future hair-care product formulation.

This review discusses the various roles of RANK signaling in bone remodeling, immune function, and epithelial differentiation, highlighting its potential involvement in cancer mechanisms; it reports no new clinical results.

This review discusses the variety of skin conditions linked to eating disorders and emphasizes that resolving these skin issues often requires treating the underlying disorder.

This study developed a rapid, cost-effective three-dimensional skin equivalent model using human dermal fibroblasts, collagen, and hair follicles, which closely resembles natural human skin and can be used for autologous transplantation.

This manuscript reviews the latest understanding of alopecia areata's pathogenesis, highlighting the roles of genetic, immunological, and environmental factors, with a focus on immune responses involving IFN-γ and cytotoxic CD8+ T-cells as key contributors to hair follicle inflammation and function disruption without follicle destruction.

This study demonstrated a method for large-scale preparation of self-sorted hair follicle germs in vitro, which successfully generated hair follicles when transplanted into the skin of nude mice.

Alopecia areata seriously lowers quality of life, especially affecting self-image, mental health, and social life.

This study reported the successful isolation of epithelial stem cells from mouse embryonic skin using a simple culture method, with the cells showing the potential to differentiate into multiple cell types.

This study found that nuclear androgen receptors are not necessary for androgen self-administration, suggesting that plasma membrane receptors might be involved.

This study concluded that bleach treatment partly transforms the hydrophobic top layer of human hair cuticles into a hydrophilic surface with clustered cysteic acid, visualized at the nano-scale using dynamic Chemical Force Microscopy.

This review discusses current hypotheses about cicatricial alopecia's pathogenesis, including lymphocyte-mediated mechanisms and sebaceous gland defects, and reports no new results, emphasizing the need for systematic research.

This review discusses advances in understanding epidermal biology and pathology over the past two decades and highlights the significant progress yet acknowledges that much remains to be discovered; no new clinical results are reported.

This study found that women with androgenetic alopecia report various negative impacts on their lives due to hair thinning, highlighting emotional concerns and dissatisfaction with appearance.