Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that androgenetic alopecia negatively impacts the emotional and social well-being of Polish men, particularly younger individuals, with 66.7% reporting a significant effect on self-esteem.

This study developed a convolutional neural network model for non-invasive diagnosis of androgenetic alopecia using dermoscopic images, demonstrating potential accuracy and scalability while highlighting the importance of model interpretability for clinical use.

This review discusses the characteristics, biomaterials, and tissue engineering methods for adipose-derived stem cells in a 3D environment, highlighting their potential in regenerative medicine without presenting new clinical results.

This study found that the transcription factor Gata6 regulates the sebaceous duct lineage identity and plays a crucial role in epidermal wound healing by enabling dedifferentiation and broader lineage capabilities in post-mitotic cells.

This study found that the Cutaneous Lupus Disease Area and Severity Index (CLASI) is correlated with both physician-assessed and patient-reported outcomes in cutaneous lupus erythematosus, particularly highlighting concerns about body image in visible areas.

This study found that conditioned medium from keratinocytes improved the hair-inductive properties of cultured dermal papilla cells, suggesting potential for enhancing hair follicle regeneration.

This study developed a technique to limit genetic recombination to regulatory T cells to investigate whether self-tolerance is maintained in non-lymphoid tissues, an area previously not well understood.

In this study, the researchers discovered that specific polyamine depletion enhances stemness in hair follicle stem cells through a mechanism independent of mRNA translation.

This study established a rat model of radiation-induced dermatitis using 90 Gy irradiation, which may aid in exploring new treatments and understanding the pathology, particularly highlighting autophagy regulation as a potential therapeutic target.

This study found that dermal stem cells from granulation tissue promoted wound healing and reduced fibrosis in a combined radiation and skin wound mouse model.

Caffeine can damage hearing cells and affect hearing recovery after ear trauma.

In this study, researchers created nanowhiskers from crab shell-derived nanochitin that self-assembled into vibrant structural colors within a film. The material, sensitive to environmental changes, shows potential as a food freshness indicator and a sustainable dye for cosmetics due to chitin's biocompatibility.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

This review discusses coordinated management strategies for polycystic ovary syndrome across various levels of care but reports no new clinical results.

This study found that patients with alopecia areata have poor knowledge about their condition, but they maintain positive attitudes and engage in proactive practices for disease management, underlining the need for enhanced patient education to improve outcomes.

In this study, researchers developed a microfluidics-based method to generate hair follicle germs on a large scale for potential hair regeneration therapies, demonstrating efficient hair follicle regeneration following transplantation into mice.

In this randomized controlled trial involving breast cancer patients undergoing chemotherapy, this study investigated the efficacy of low-level light therapy for preventing hair loss, measuring outcomes like hair count and patient quality of life, but the abstract does not report specific results.

This study found that human hair exhibits significant deformation in its intermediate filaments under strain, with recovery taking about 1000 minutes, suggesting a self-healing period post-mechanical stress. Additionally, cuticle scales deform much less than the cortex, and the Poisson ratio aligns with soft matter properties.

In this study, researchers highlighted the complexity of managing psychocutaneous disorders, emphasizing the need for a multidisciplinary approach involving dermatologists, psychiatrists, family physicians, and social support to address associated psychiatric diagnoses, risk factors like suicide, and ensure effective treatment.

This study utilized a novel mass spectrometry imaging technique to demonstrate that argan, avocado, and coconut oils are incorporated into hair fibers during cosmetic treatments, supporting their potential use in formulations for enhancing hair health and treating conditions like alopecia.

Human hair follicles can provide stem cells for regenerative medicine.

This study reports that human eccrine sweat gland cells are capable of forming a stratified epidermis, suggesting they may serve as an additional source of keratinocytes for skin repair.

This review highlights recent advances in chitosan-based nanoparticles (CS NPs) for drug delivery, discussing their modifications, preparation methods, production with organic and inorganic materials, and their latest implementations in the field, emphasizing the role of CS NPs in improving drug transport and release properties.

This review examines the complex mechanisms that regulate skin stem cell development, activation, and differentiation, emphasizing the molecular signaling pathways that influence their fate and contribute to skin homeostasis.

This article reviews the functions and locations of skin stem cells and their role in regeneration and differentiation, relating age-associated skin changes to decreased stem cell functionality; it reports no new experimental findings.

This review discusses the use of human-to-mouse xenografting to study human skin processes in vivo, highlighting its importance for understanding skin regeneration and pathology while identifying knowledge gaps and challenges in applying these findings to human skin.

In this study, researchers discovered that the HrasG12V oncogenic mutation in murine skin epithelial cells initially promotes progenitor cell renewal but later leads to a balanced differentiation, stabilizing clone growth.

In this study, researchers observed that oncogenic HrasG12V in single murine epidermal cells leads to an initial increase in progenitor cell renewal, but ultimately results in balanced cell fate choices that limit clone growth.

This study found that in murine dermis, fibroblast state switching between proliferation and ECM deposition plays a crucial role in tissue architecture and wound healing.

This review examines integrins as pharmacological targets, discussing current integrin-based therapies and emphasizing the need to understand integrin mechanisms for successful drug development, without reporting new clinical results.