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Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Microneedling can help stimulate hair growth, especially when used with other treatments, but it's not better than existing therapies.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

Nearly all elderly nursing home residents had a skin disease, with dry skin being the most common.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.

Most treatments for lichen planopilaris were found to be generally unsatisfactory.

Plasmacytoid dendritic cells are a key factor in causing hair loss in alopecia areata and could help differentiate it from other hair loss conditions.

Some natural compounds can protect fish ear cells from damage by certain antibiotics without affecting the antibiotics' ability to fight infections.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

Flutamide effectively treats female pattern hair loss with low doses showing good liver tolerance.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

About 8.5% of women in Salvador, Brazil, have Polycystic Ovary Syndrome.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.

More pediatric-specific research and guidelines are needed to improve hidradenitis suppurativa treatment in children and adolescents.

Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.

The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Type I interferons play a key role in the development of various skin diseases.

Apremilast improved symptoms in patients with severe skin conditions.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.